NCT04706273

Brief Summary

This study will confirm device efficacy and safety in the clinical setting after the launch of the GORE® VIABAHN® Endoprosthesis for the treatment of symptomatic peripheral arterial disease in the superficial femoral arteries.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
321

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2016

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

August 25, 2016

Completed
2.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 11, 2019

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

January 8, 2021

Completed
4 days until next milestone

First Posted

Study publicly available on registry

January 12, 2021

Completed
1.9 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 14, 2022

Completed
1.8 years until next milestone

Results Posted

Study results publicly available

September 20, 2024

Completed
Last Updated

September 20, 2024

Status Verified

October 1, 2023

Enrollment Period

2.9 years

First QC Date

January 8, 2021

Results QC Date

October 10, 2023

Last Update Submit

May 21, 2024

Conditions

Outcome Measures

Primary Outcomes (4)

  • Primary Assisted Patency

    Primary assisted patency is defined as hemodynamic evidence of flow through a device that had not required a Target lesion revascularization to restore flow after total occlusion. Kaplan-Meier estimates created for each time point.

    12 and 24 months

  • Freedom From Target Lesion Revascularization

    Revascularization for restenosis or occlusion of the target lesion. Kaplan-Meier estimates created for each time point.

    1, 12 and 24 months

  • Number of Participants With One or More Device- or Procedure-related Serious Adverse Events and Deficiencies

    The number and proportion of the subjects for whom the occurrence of serious adverse events were reported.

    Procedure day, 1, 12, 24, 36, 48 and 60 months

  • Number of Participants With a Stent Fracture

    The number and proportion of stent fracture as assessed by Core lab

    Month 12, 24, 36, 48 and 60

Study Arms (1)

GORE® VIABAHN® Endoprosthesis

Participants with symptomatic peripheral arterial disease in superficial femoral artery lesions.

Device: GORE® VIABAHN® Endoprosthesis

Interventions

Participants receiving the GORE® VIABAHN® Endoprosthesis

GORE® VIABAHN® Endoprosthesis

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients with symptomatic peripheral arterial disease in superficial femoral artery lesions in Japan

You may qualify if:

  • Symptomatic peripheral arterial disease in superficial femoral artery lesions

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Kansai Rousai

Amagasaki, Hyōgo, Japan

Location

Related Publications (1)

  • Iida O, Ohki T, Soga Y, Suematsu N, Nakama T, Yamaoka T, Tobita K, Ichihashi S. Five-year outcomes of the GORE VIABAHN Endoprosthesis for the treatment of complex femoropopliteal lesions from a Japanese postmarket surveillance study. Vasc Med. 2024 Aug;29(4):416-423. doi: 10.1177/1358863X241233528. Epub 2024 Mar 27.

MeSH Terms

Conditions

Peripheral Arterial Disease

Condition Hierarchy (Ancestors)

AtherosclerosisArteriosclerosisArterial Occlusive DiseasesVascular DiseasesCardiovascular DiseasesPeripheral Vascular Diseases

Results Point of Contact

Title
Eric Novak
Organization
W. L. Gore & Associates

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
OTHER
Restrictive Agreement
Yes

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 8, 2021

First Posted

January 12, 2021

Study Start

August 25, 2016

Primary Completion

July 11, 2019

Study Completion

December 14, 2022

Last Updated

September 20, 2024

Results First Posted

September 20, 2024

Record last verified: 2023-10

Locations