Behavioral and Neurophysiological Effects of Multichannel Executive Network tDCS Combined With Preferred Music Stimulation
1 other identifier
interventional
24
1 country
1
Brief Summary
This study aims at comparing the effects of transcranial direct current stimulation combined with music on neurophysiological outcomes in healthy participants. This study also aims to evaluate the effects of tDCS combined with music on cognition.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for phase_1 healthy
Started Oct 2019
Longer than P75 for phase_1 healthy
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 4, 2019
CompletedFirst Submitted
Initial submission to the registry
January 7, 2021
CompletedFirst Posted
Study publicly available on registry
January 12, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
December 30, 2021
CompletedStudy Completion
Last participant's last visit for all outcomes
December 30, 2021
CompletedAugust 5, 2024
August 1, 2024
2.2 years
January 7, 2021
August 2, 2024
Conditions
Outcome Measures
Primary Outcomes (1)
3-back
The subject is presented with a sequence of stimuli, and the task consists of indicating when the current stimulus matches the one from 3 steps earlier in the sequence.
It will be measured over the course of four weeks
Secondary Outcomes (3)
Stroop
It will be measured over the course of four weeks
EEG - alpha power
It will be measured over the course of four weeks
EEG - beta power
It will be measured over the course of four weeks
Study Arms (4)
tDCS/music
EXPERIMENTALactive tDCS combined with music
sham tDCS/music
EXPERIMENTALSham tDCS combined with music
tDCS/white noise
EXPERIMENTALactive tDCS combined with white noise
sham tDCS/white noise
EXPERIMENTALsham tDCS combined with white noise
Interventions
Multi-channel tDCS will be applied over the executive network for 20 minutes at 4mA
Sham tDCS will consist of applying the same parameters as for active but the corresponding device will be turned off after 30 seconds as to simulate the initial sensation of the active current. A current of 2mA will still be used (but turned off after 30 sec). The electrodes that will be used will be the same as for the active tDCS condition and the electrodes placement as well.
Subjects will listen to a white noise for 20 minutes
Eligibility Criteria
You may qualify if:
- healthy adults
You may not qualify if:
- neurological disorders
- psychiatric disorders
- contra-indication to tDCS (eg, metallic brain implant, pacemaker)
- pregnancy
- alcool abuse
- active smoker
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University Hospital of Liege
Liège, 4000, Belgium
MeSH Terms
Interventions
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- phase 1
- Allocation
- RANDOMIZED
- Masking
- TRIPLE
- Who Masked
- PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
- Purpose
- TREATMENT
- Intervention Model
- CROSSOVER
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Principal Investigator
Study Record Dates
First Submitted
January 7, 2021
First Posted
January 12, 2021
Study Start
October 4, 2019
Primary Completion
December 30, 2021
Study Completion
December 30, 2021
Last Updated
August 5, 2024
Record last verified: 2024-08