NCT04702035|Completed
Walking Pattern Characteristics in Normal Pressure Hydrocephalus
NPH wearables
Loading search results
NPH wearables
Sponsor study identifier
interventional
60
1 country
1
Study Start
January 1, 2018
Actual (reported)Primary Completion
April 25, 2024
Actual (reported)Study Completion
April 25, 2024
Actual (reported)20 patients who are diagnosed with NPH receive a set of 5 wearable gyroscopes (IMUs, ZurichMove sensors) for a period of 3 days for measurement and characterization of their walking in an ambulatory setting. At a follow-up 2 weeks to 6 months after CSF diversion surgery, the examination is repeated and improvement is measured. The data will be compared with a healthy group of 20 age- and gender-matched individuals as well a a group of 20 young individuals.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
April 25, 2024
Actual (reported)Click on a node to explore related trials.
Some registry-reported names shown below are not yet linked in this graph.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
January 1, 2018
Actual (reported)November 15, 2020
Actual (reported)January 8, 2021
Actual (reported)April 25, 2024
Actual (reported)April 25, 2024
Actual (reported)Walking characteristics
Complex walking pattern comprising of stride length, width, frequency (altogether one parameter)
Between 2 weeks to 6 months after CSF diversion surgery
4 minutes timed Walk test
immediately after fixation of IMUs
180 degree turnaround test
immediately after fixation of IMUs
Kiefer score
before surgery
Kiefer score
after surgery (range 2 weeks to 6 months)
Stein and Langfitt score
before surgery
20 patients with completed diagnostics concerning NPH, in which the indication for implantation of a VP shunt for NPH treatment was found by the responsible surgeon independently from the study.
20 volunteers, matched with group 1 concerning sex and age.
All participants receive a set of 5 wearable IMUs for a period of 3 days. The IMUs are fixed at both wrists, ankles and one over the sternum. A 10-meter walking test, 180 degree turnaround test and normal walking at home are performed. Afterwards, the IMUs are removed for data extraction and evaluation. The patient group is examined a second time after CSF diversion surgery.
Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.
Dept. of Neurosurgery, Zurich University Hospital
Zurich, 8091, Switzerland
Renggli D, Graf C, Tachatos N, Singh N, Meboldt M, Taylor WR, Stieglitz L, Schmid Daners M. Wearable Inertial Measurement Units for Assessing Gait in Real-World Environments. Front Physiol. 2020 Feb 20;11:90. doi: 10.3389/fphys.2020.00090. eCollection 2020.
60 participants (actual enrollment reported by the registry).
First Submitted
November 15, 2020
First Posted
January 8, 2021
Study Start
January 1, 2018
Change in Cognition and Frailty After Shunt Surgery in Idiopathic Normal Pressure Hydrocephalus (iNPH)
20 volunteers, matched with group 1 concerning sex only and between 18 and 40 years old.
Contact the study team to confirm eligibility.
Primary Completion
April 25, 2024
Actual (reported)Study Completion
April 25, 2024
Actual (reported)Last Updated
April 26, 2024
Record last verified: 2024-04
Sharing of data with other researchers is not intended.
Download the complete ClinicalTrials.gov record imported by Syfrah, including fields not shown in this page. The registry may contain a newer revision.
Source: ClinicalTrials.gov.
JSON downloads include source attribution and retrieval details alongside the unchanged original record or the separately normalized values.
Source retrieved: