NCT04690478

Brief Summary

Recruit patients with essential hypertension and randomly divide them into three groups. For 24 months, observe the patient's blood pressure level and blood pressure compliance rate,Risk assessment, etc.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
1,050

participants targeted

Target at P75+ for not_applicable hypertension

Timeline
Completed

Started Jun 2020

Typical duration for not_applicable hypertension

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2020

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

December 8, 2020

Completed
22 days until next milestone

First Posted

Study publicly available on registry

December 30, 2020

Completed
2.2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2023

Completed
Last Updated

February 17, 2022

Status Verified

February 1, 2022

Enrollment Period

2.8 years

First QC Date

December 8, 2020

Last Update Submit

February 16, 2022

Conditions

Keywords

Hypertension;Telemedicine;Remote blood pressure monitoring

Outcome Measures

Primary Outcomes (7)

  • Blood pressure level(SBP and DBP)

    Blood pressure level(SBP and DBP)

    2years

  • Blood pressure compliance rate(SBP and DBP)

    Blood pressure compliance rate(SBP and DBP)

    2years

  • Cardiovascular risk assessment

    Cardiovascular risk assessment

    2years

  • Economic benefit

    Compare economic benefit among the three groups by counting the cost of hypertension treatment and the cost of hospitalization due to complications of hypertension of patients in every group.

    2years

  • improved level of quality of life

    Compare improved level of quality of life among the three groups by counting the proportions of patients with improvement of lifestyle and living habits in every group.The content of improvement of lifestyle and living habits mainly including reduction of the frequency and amount of smoking, drinking, high-salt diet and high-fat diet, increase of the frequency and amount of exercise, and so on.

    2years

  • Clinical prognosis assessment

    Compare clinical prognosis among the three groups by counting incidence of non-fatal acute myocardial infarction, non-fatal stroke, hospitalization for unstable angina, hospitalization for worsening heart failure in every group.

    2years

  • Therapeutic compliance

    Compare therapeutic compliance among the three groups by counting the proportions of patients taking medication on time and regularly receiving follow-up at office in every group.

    2years

Study Arms (3)

Remote blood pressure management group

EXPERIMENTAL

Remote blood pressure management group through remote blood pressure management the platform realizes functions such as automatic upload of patient measurement data, intelligent analysis, and early warning reminders

Device: Electronic remote blood pressure monitor

Non-remote blood pressure management group

OTHER

Non-remote blood pressure management group is distributed a set of ordinary household electronic sphygmomanometer, and the blood pressure is recorded by themselves at home following routine community office follow-up

Device: Ordinary household electronic sphygmomanometer

Routine blood pressure management group

OTHER

Routine blood pressure management group follows routine community office follow-up and uses office electronic sphygmomanometer to measure blood pressure

Device: Office electronic sphygmomanometer

Interventions

Remote blood pressure management group through remote blood pressure management the platform realizes functions such as automatic upload of patient measurement data, intelligent analysis, and early warning reminders

Remote blood pressure management group

One group is distributed a set of ordinary household electronic sphygmomanometer, and the blood pressure is recorded by themselves at home following routine community office follow-up

Non-remote blood pressure management group

One group follows routine community office follow-up and uses office electronic sphygmomanometer to measure blood pressure

Routine blood pressure management group

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Clinical diagnosis of primary hypertension
  • Must be aged at ≥18 years old and ≤75 years old
  • Must have a smart phone and have the ability to use smart devices
  • Must be local permanent resident population who volunteered to participate in the study and received a 2-year follow-up
  • Must sign informed consent

You may not qualify if:

  • Participated in other clinical trials within 4 weeks before the start of this study
  • The systolic blood pressure in the office was ≥180 mmHg, and/or the diastolic blood pressure was ≥110 mmHg
  • Uremia, creatinine\>250umol/l
  • History of acute heart disease in the past three months
  • Terminal diseases such as malignant tumors
  • Severe cognitive impairment
  • Severe diabetes patients (glycated hemoglobin\>11%)
  • Severe valvular heart disease, cardiomyopathy, and poor heart function
  • Atrial fibrillation and atrioventricular block
  • Arm circumference \>35cm or \<26cm
  • Spouse or relatives have been included in this research
  • Pregnant or breastfeeding women
  • Live in an unfixed state

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Remote electronic sphygmomanometer

Qingdao, Shandong, 266000, China

RECRUITING

Related Publications (1)

  • Teng TQ, Sun GX, Yu ZY, Liu ZS, Wang T, Wu Q, Qin RR, Wang MM, Chen R, Xu JC, Zhang N, Song BX, Liu X, Zhang YY, Yu HC. Efficiency of remote monitoring and guidance in blood pressure management: a randomized controlled trial : The role of remote monitoring in improving hypertension management. BMC Med. 2025 Aug 5;23(1):459. doi: 10.1186/s12916-025-04278-6.

MeSH Terms

Conditions

Hypertension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Study Officials

  • Yu haichu, master

    Affiliated Cardiovascular Hospital of Qingdao University

    STUDY CHAIR

Central Study Contacts

Yu haichu, master

CONTACT

Sun guixia, master

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 8, 2020

First Posted

December 30, 2020

Study Start

June 1, 2020

Primary Completion

March 31, 2023

Study Completion

June 30, 2023

Last Updated

February 17, 2022

Record last verified: 2022-02

Locations