NCT04685122

Brief Summary

To compare the accuracy of four lens diameter measurement methods and to study the influencing factors of intraocular lens deviation after operation

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
60

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Nov 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

November 1, 2020

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

December 16, 2020

Completed
12 days until next milestone

First Posted

Study publicly available on registry

December 28, 2020

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2021

Completed
Last Updated

December 28, 2020

Status Verified

December 1, 2020

Enrollment Period

8 months

First QC Date

December 16, 2020

Last Update Submit

December 22, 2020

Conditions

Outcome Measures

Primary Outcomes (7)

  • Lens diameter

    Measured by related instruments before surgery and calculated by the circumference of the tension ring in the surgical video screenshot

    through study completion, an average of 1 year

  • The eccentric distance of the intraocular lens

    The distance between the center of the lens plane and the center of the pupil plane is the eccentric distance of the lens.

    1 week postoperation

  • The eccentric distance of the intraocular lens

    The distance between the center of the lens plane and the center of the pupil plane is the eccentric distance of the lens.

    1 month postoperation

  • The eccentric distance of the intraocular lens

    The distance between the center of the lens plane and the center of the pupil plane is the eccentric distance of the lens.

    3 month postoperation

  • The tilt angle of the intraocular lens

    The angle between the plane of the lens and the plane of the pupil is the inclination of the lens

    1 week postoperation

  • The tilt angle of the intraocular lens

    The angle between the plane of the lens and the plane of the pupil is the inclination of the lens

    1 month postoperation

  • The tilt angle of the intraocular lens

    The angle between the plane of the lens and the plane of the pupil is the inclination of the lens

    3 month postoperation

Interventions

Phacoemulsification and intraocular lens implantation for cataract

Eligibility Criteria

Age20 Years - 88 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

People whose subluxation of the lens is less than 180 degrees

You may qualify if:

  • (1) Subluxation of the lens is less than 180 degrees; (2) Part of the edge of the lens can be seen in the pupil area after the pupil is dilated

You may not qualify if:

  • (1) Total dislocation of the lens to the vitreous cavity (2) Patients with small eyeballs and small eyelid fissures (3) Patients younger than 18 years old (4) Congenital cataracts in both eyes (5) Corneal dystrophy or endothelial cell insufficiency (6) Chronic uvea Inflammation (7) Progressive fundus disease (8) Fragile capsular bag (9) Retinitis pigmentosa or pseudocapsular exfoliation syndrome

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Second Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, 310009, China

Location

MeSH Terms

Conditions

Lens Subluxation

Interventions

PhacoemulsificationLens Implantation, Intraocular

Condition Hierarchy (Ancestors)

Lens DiseasesEye Diseases

Intervention Hierarchy (Ancestors)

Cataract ExtractionRefractive Surgical ProceduresOphthalmologic Surgical ProceduresSurgical Procedures, OperativeUltrasonic Surgical Procedures

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

December 16, 2020

First Posted

December 28, 2020

Study Start

November 1, 2020

Primary Completion

July 1, 2021

Study Completion

July 1, 2021

Last Updated

December 28, 2020

Record last verified: 2020-12

Data Sharing

IPD Sharing
Will not share

Locations