HIV Acquisition and Life Course of Born-abroad Men Who Have Sex With Men Living in Ile-de-France: the GANYMEDE Study

NCT04684758 | Completed

• 1 other identifier: ANRS 14058
• Study Type: observational
• Target: 1,048
• Locations: 1 country
• Sites: 1

Brief Summary

In France, men who have sex with men (MSM) born abroad are the most affected population by HIV, in terms of HIV incidence and prevalence of undiagnosed infections. Close to 50% of born-abroad HIV-infected MSM are living in the region of Ile-de-France, which is the metropolitan area of Paris. Recent European data, not including France, suggest that born-abroad MSM have the highest rate of post-migration HIV acquisition. Many vulnerability factors could explain le burden of HIV in this group of the population. A better understanding of vulnerability factors related to post-migration HIV acquisition should allow to improve HIV prevention and screening strategies among born-abroad MSM living in France. This, in turn, should reduce the burden of HIV in this population in France.

Conditions

Men Who Have Sex With Men; People Living With HIV

Outcome Measures

Primary Outcomes (1)

• Post-migration proportion of HIV acquisition in born-abroad HIV-positive MSM living in Ile-de-France

  Estimation of the post-migration proportion of HIV acquisition in born-abroad HIV-positive MSM living in Ile-de-France (proportion of participants, n (%))

  Through study completion, an average of 12 months

Secondary Outcomes (1)

• Timing of HIV infection for people infected in France

  Through study completion, an average of 12 months

Other Outcomes (6)

• Phylogenetic analysis in participants having acquired HIV before and after the migration, between them and with other populations

  Through study completion, an average of 12 months

• Motivations and migratory processes

  Through study completion, an average of 12 months

• Vulnerability factors

  Through study completion, an average of 12 months

Interventions

Self-completion of a questionnaire OTHER

The questionnaire will be translated into 5 languages (English, Spanish, Portuguese, Arabic, and Russian) in order to allow almost all of the participants to answer the survey themselves, without assistance. In order to not exclude those who cannot read, or those who do not master any of the 6 languages offered, the questionnaire may be administered with the assistance of a member of the research team of the associated center, including through a telephone interpretation service, if necessary.

Eligibility Criteria

• Age: 18 Years - 99 Years
• Sex: male
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

* Cis-gender men who report having sex with men; * Over 18 years of age; * Type 1 HIV infected; * Born in a country other than France and arrived in France at the age of 15 at the earliest;

You may qualify if:

• Cis-gender men who report having sex with men;
• Over 18 years of age;
• Type 1 HIV infected;
• Born in a country other than France and arrived in France at the age of 15 at the earliest;
• Followed in Ile-de-France for their HIV infection and having consulted at least once in the participating center during the last 12 months;
• Non-opposition to the collection of their health data, after being well informed of the study and the patient rights in accordance with RGPD and LIL (French regulation)

You may not qualify if:

• Somatic or psychiatric pathology making it impossible to participate in an investigation;
• Communication disorder making it impossible to read (or oral responses in the event of assisted questionnaire completion).

Sponsors & Collaborators

• ANRS, Emerging Infectious Diseases: lead
• Institut National de la Santé Et de la Recherche Médicale, France: collaborator

Study Sites (1)

Hôpital Pitié-Salpêtrière, AP-HP, Institut Pierre Louis d'Épidémiologie et de Santé Publique (iPLESP), INSERM 1136

Paris, 75013, France

Location

MeSH Terms

Conditions

Homosexuality

Condition Hierarchy (Ancestors)

Sexuality; Sexual Behavior; Behavior

Study Design

• Study Type: observational
• Observational Model: ECOLOGIC OR COMMUNITY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER GOV
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: December 3, 2020
• First Posted: December 28, 2020
• Study Start: April 14, 2021
• Primary Completion: June 30, 2022
• Study Completion: June 30, 2022
• Last Updated: July 22, 2022

Record last verified: 2022-07

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)