NCT04681222

Brief Summary

The ultrasound-guided approach for the blockade of articular branches of femoral and obturator nerves, pericapsular nerve group (PENG) block, is an effective method for postoperative analgesia in hip surgeries.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
22

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Jan 2019

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2019

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
12 months until next milestone

First Submitted

Initial submission to the registry

December 18, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

December 23, 2020

Completed
Last Updated

December 24, 2020

Status Verified

December 1, 2020

Enrollment Period

12 months

First QC Date

December 18, 2020

Last Update Submit

December 22, 2020

Conditions

Postoperative Pain

Keywords

CoxarthrosisRegional AnesthesiaTotal Hip Replacement

Outcome Measures

Primary Outcomes (1)

  • First analgesic demand

    The time interval from PENG blocks to the first analgesic demand.

    24 hours

Secondary Outcomes (3)

  • Opioid consumption

    24 hours

  • Numeric Rating Scale

    24 hours

  • Nonsteroidal Anti-inflammatory Drugs (NSAID)

    24 hours

Study Arms (2)

LFCN

Patients received LFCN + PENG blocks

Procedure: LFCN

Wound Infiltration

Patients received wound infiltration + PENG blocks

Procedure: Wound infiltration

Interventions

LFCNPROCEDURE

LFCN block was performed in combination with PENG block

LFCN
Wound infiltrationPROCEDURE

Wound infiltration was performed in combination with PENG block

Wound Infiltration

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients underwent total hip arthroplasty with the diagnosis of coxarthrosis, and those received PENG blocks for postoperative analgesia combined with whether LFCN block or wound infiltration.

You may qualify if:

  • Coxarthrosis
  • Total hip replacement
  • Patients agreed to receive PENG block
  • LFCN or wound infiltration performed combined with PENG blocks

You may not qualify if:

  • Other kinds of hip surgeries
  • Total hip replacement performed for other indications
  • Patients refused to receive PENG block

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Derince Training and Research Hospital

Kocaeli, Derince, 41900, Turkey (Türkiye)

Location

Related Publications (5)

  • Giron-Arango L, Peng PWH, Chin KJ, Brull R, Perlas A. Pericapsular Nerve Group (PENG) Block for Hip Fracture. Reg Anesth Pain Med. 2018 Nov;43(8):859-863. doi: 10.1097/AAP.0000000000000847.

    PMID: 30063657BACKGROUND

  • Roy R, Agarwal G, Pradhan C, Kuanar D. Total postoperative analgesia for hip surgeries, PENG block with LFCN block. Reg Anesth Pain Med. 2019 Mar 28:rapm-2019-100454. doi: 10.1136/rapm-2019-100454. Online ahead of print. No abstract available.

    PMID: 30923252BACKGROUND

  • Nersesjan M, Hagi-Pedersen D, Andersen JH, Mathiesen O, Dahl JB, Broeng L, Thybo KH. Sensory distribution of the lateral femoral cutaneous nerve block - a randomised, blinded trial. Acta Anaesthesiol Scand. 2018 Jul;62(6):863-873. doi: 10.1111/aas.13091. Epub 2018 Feb 21.

    PMID: 29468642BACKGROUND

  • Giron-Arango L, Roques V, Peng P. Reply To Dr Roy et al: Total postoperative analgesia for hip surgeries: PENG block with LFCN block. Reg Anesth Pain Med. 2019 Mar 28:rapm-2019-100505. doi: 10.1136/rapm-2019-100505. Online ahead of print. No abstract available.

    PMID: 30923249BACKGROUND

  • Mistry T, Sonawane KB, Kuppusamy E. PENG block: points to ponder. Reg Anesth Pain Med. 2019 Mar;44(3):423-424. doi: 10.1136/rapm-2018-100327. Epub 2019 Jan 11. No abstract available.

    PMID: 30635514BACKGROUND

MeSH Terms

Conditions

Pain, PostoperativeOsteoarthritis, Hip

Condition Hierarchy (Ancestors)

Postoperative ComplicationsPathologic ProcessesPathological Conditions, Signs and SymptomsPainNeurologic ManifestationsSigns and SymptomsOsteoarthritisArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Medical Doctor, Associate Professor, Principal Investigator

Study Record Dates

First Submitted

December 18, 2020

First Posted

December 23, 2020

Study Start

January 1, 2019

Primary Completion

December 31, 2019

Study Completion

December 31, 2019

Last Updated

December 24, 2020

Record last verified: 2020-12

Locations

TU(1)