NCT04676152

Brief Summary

This is a prospective, nonrandomized multi-center study for the investigation of noninvasive sphygmomanometers. The purpose of the study is to validate the clinical performance of the Masimo noninvasive blood pressure device compared to reference auscultatory measurements.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
106

participants targeted

Target at P75+ for not_applicable healthy

Timeline
Completed

Started Oct 2020

Shorter than P25 for not_applicable healthy

Geographic Reach
1 country

2 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 5, 2020

Completed
28 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 2, 2020

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 2, 2020

Completed
3 days until next milestone

First Submitted

Initial submission to the registry

November 5, 2020

Completed
1 month until next milestone

First Posted

Study publicly available on registry

December 19, 2020

Completed
2.7 years until next milestone

Results Posted

Study results publicly available

September 13, 2023

Completed
Last Updated

January 8, 2024

Status Verified

January 1, 2024

Enrollment Period

28 days

First QC Date

November 5, 2020

Results QC Date

June 29, 2023

Last Update Submit

January 3, 2024

Conditions

Outcome Measures

Primary Outcomes (1)

  • Mean and Standard Deviation of Differences Between Masimo NIBP Device and Manual Sphygmomanometer Measurements.

    Performance will be determined by calculating the mean and standard deviation of the differences between the systolic and diastolic blood pressure measurements obtained from Masimo NIBP device and manual sphygmomanometer.

    1 hour

Study Arms (1)

Test subjects

EXPERIMENTAL

All subjects enrolled had blood pressure measurements taken using the noninvasive blood pressure device.

Device: Masimo Noninvasive Blood Pressure Device

Interventions

Non-invasive blood pressure device

Test subjects

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18 years and older
  • Site 1; Stage 1 only: Subjects with a history of hypertension (\> 140/85 mmHg) or hypotension (\< 100/60 mmHg) within the last 3 months. Stage 2 only: No criterion for blood pressure
  • Site 2; Stage 1 and 2: Subjects with systolic blood pressure \< 140/90 mmHg.
  • Ability to provide informed consent

You may not qualify if:

  • Febrile subjects
  • Subjects displaying respiratory symptoms, or with suspected respiratory illness
  • Subjects whose skin is not intact, e.g. wounded, in or at the vicinity of the cuff placement site
  • Subjects with removed axillary lymph nodes or mastectomies
  • Subjects with peripheral artery disease
  • Pregnant women (patient reported)
  • Subjects deemed not suitable for the study at the discretion of the investigator

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

Site 2

Irvine, California, 92618, United States

Location

Site 1

Lomita, California, 90717, United States

Location

MeSH Terms

Conditions

HypertensionHypotension

Condition Hierarchy (Ancestors)

Vascular DiseasesCardiovascular Diseases

Results Point of Contact

Title
Chelsea Frank
Organization
Masimo Corporation

Publication Agreements

PI is Sponsor Employee
No
Restriction Type
GT60
Restrictive Agreement
Yes

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
OTHER
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 5, 2020

First Posted

December 19, 2020

Study Start

October 5, 2020

Primary Completion

November 2, 2020

Study Completion

November 2, 2020

Last Updated

January 8, 2024

Results First Posted

September 13, 2023

Record last verified: 2024-01

Locations