The Effect of Chewing the Tapioca Pearls in Bubble Tea Drinks

NCT04670341 | Completed DMC

• 1 other identifier: FKGUGM1
• Study Type: interventional
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

Bubble tea drinks contain tea and tapioca pearls. Chewing tapioca pearls in bubble tea drinks may increase salivary components. Because of its proteins, inorganic components, and enzymes, saliva plays an important role in the body's defense against bacteria and viruses. This study aims to analyze the effect of chewing the tapioca pearls in bubble tea drinks on salivary C-reactive protein (CRP) and calcium (Ca) levels.

Conditions

Saliva

Keywords

bubble tea; salivary C-reactive protein; salivary calcium

Outcome Measures

Primary Outcomes (1)

• Salivary C-reactive protein (CRP) level

  Salivary CRP level was measured on the first day before chewing tapioca peals in the bubble tea drinks and drink tea. Salivary CRP level was measured on the third day after drink bubble tea and tea without tapioca pearls

  3 days

Secondary Outcomes (1)

• Calcium (Ca) level

  3 days

Study Arms (2)

chewing tapioca pearls in the bubble tea drinks

EXPERIMENTAL

In the first week, the subjects drink as much as 100 ml of bubble tea over a span of 5 minutes once a day for 3 days

Other: chewing tapioca pearls in bubble tea drinks

drink tea without chewing tapioca pearls

PLACEBO COMPARATOR

In the second week, the subjects drink tea without tapioca pearls as much as 100 ml for 5 minutes per day for 3 days.

Other: drink tea without chewing tapioca pearls

Interventions

chewing tapioca pearls in bubble tea drinks OTHER

Saliva was collected on the first day before bubble tea consumption (pretest) and on the third day after bubble tea consumption (posttest); collection was conducted in the morning (09:00 a.m.-12.00 p.m.).

chewing tapioca pearls in the bubble tea drinks

drink tea without chewing tapioca pearls OTHER

Saliva was collected on the first day before drink tea without tapioca pearl (pretest) and on the third day after tea consumption (posttest); collection was conducted in the morning (09:00 a.m.-12.00 p.m.).

drink tea without chewing tapioca pearls

Eligibility Criteria

• Age: 18 Years - 25 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• good Oral Hygiene Index-Simplified (OHI-S) score

You may not qualify if:

• taking medication
• a history of dry mouth
• smoking
• systemic disease

Sponsors & Collaborators

• Gadjah Mada University: lead

Study Sites (1)

Faculty of Dentistry, Universitas Gadjah Mada

Yogyakarta, 55281, Indonesia

Location

Related Publications (1)

• Handajani J, Kusumajati D, Fathiyah H, Susilowati H, Tandelilin RTC. Quality improvement of saliva by chewing tapioca pearls in bubble tea drinks: a randomized experimental trial: (Study on salivary C-reactive protein (CRP) and calcium (Ca) levels). F1000Res. 2021 Feb 1;10:56. doi: 10.12688/f1000research.28028.2. eCollection 2021.

  PMID: 35387272 DERIVED

Related Links

• Elevated salivary C-reactive protein levels are associated with active and passive smoking in healthy youth: A pilot study

Study Officials

• Juni Handajani, PhD

  Faculty of Dentistry, Universitas Gadjah Mada

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Quality improvement of saliva by chewing tapioca pearls in bubble tea drinks

Model Details: In the first week of the experiment, subject chewing tapioca pearl inthe bubble tea. In the second week, the same subjects drink tea without chewing tapioca pearl

Study Record Dates

• First Submitted: December 9, 2020
• First Posted: December 17, 2020
• Study Start: September 17, 2020
• Primary Completion: October 17, 2020
• Study Completion: October 17, 2020
• Last Updated: December 17, 2020

Record last verified: 2020-12

Data Sharing

• IPD Sharing: Will not share

Locations

ID (1)