NCT04665245

Brief Summary

In this study, COVID-19 positive patients will be added to a bidirectional texting program to receive daily surveys about their symptoms with the infection. This data will further the understanding of COVID-19 symptom development throughout the infection period, as well as how those symptoms vary at different points of the day. This study will be a single cohort, observational study of COVID-19 patients.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
214

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Dec 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

December 10, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

December 11, 2020

Completed
4 days until next milestone

Study Start

First participant enrolled

December 15, 2020

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

May 19, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

May 19, 2021

Completed
4.7 years until next milestone

Results Posted

Study results publicly available

January 26, 2026

Completed
Last Updated

January 26, 2026

Status Verified

January 1, 2026

Enrollment Period

5 months

First QC Date

December 10, 2020

Results QC Date

January 8, 2026

Last Update Submit

January 8, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Body Temperature

    Body temperature taken each morning and evening throughout COVID-19 infection period.

    10 days

  • COVID-19 Symptoms

    Any symptoms experienced throughout COVID-19 infection period (aches, cough, decreased sense of taste and/or smell, diarrhea, difficulty breathing, headache, nausea, runny nose, sore throat, shortness of breath).

    10 days

Study Arms (1)

COVID-19 Positive Patients

The study only includes one cohort: COVID-19 positive patients. Enrollees will not receive any therapeutic intervention; participants will simply report their temperature and any symptoms experienced twice per day for 10 days.

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The study population will include patients at the University of Iowa Hospitals \& Clinics (UIHC). Approximately 5,000 people have already tested positive for COVID-19 in Johnson County alone, and numbers are continuing to increase. The University of Iowa Hospitals \& Clinics see many patients from outside of Johnson County as well.

You may qualify if:

  • Fluent in English
  • Tested positive for COVID-19

You may not qualify if:

  • Prisoners
  • Unable to provide own informed consent

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Iowa Hospitals & Clinics

Iowa City, Iowa, 52242, United States

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Results Point of Contact

Title
Shelby Francis
Organization
University of Iowa

Study Officials

  • Alberto M Segre, PhD

    University of Iowa

    PRINCIPAL INVESTIGATOR

Publication Agreements

PI is Sponsor Employee
No
Restrictive Agreement
No

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Professor, Chair, Department of Computer Science

Study Record Dates

First Submitted

December 10, 2020

First Posted

December 11, 2020

Study Start

December 15, 2020

Primary Completion

May 19, 2021

Study Completion

May 19, 2021

Last Updated

January 26, 2026

Results First Posted

January 26, 2026

Record last verified: 2026-01

Locations