NCT04662762

Brief Summary

The objective of this study was to assess the impact of a nursing intervention on therapeutic adherence in elderly patients after acute myocardial infarction compared to a control group

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
160

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2016

Longer than P75 for not_applicable

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 1, 2016

Completed
3.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 28, 2020

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 28, 2020

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

November 28, 2020

Completed
12 days until next milestone

First Posted

Study publicly available on registry

December 10, 2020

Completed
Last Updated

December 14, 2020

Status Verified

December 1, 2020

Enrollment Period

3.9 years

First QC Date

November 28, 2020

Last Update Submit

December 10, 2020

Conditions

Keywords

ElderlyNursing

Outcome Measures

Primary Outcomes (1)

  • Number of patients with therapeutic adherence

    The main outcome measured was therapeutic adherence 12 months after admission. The definition of adherence was a single measure taking into account 4 different methods (see below). Patients were considered adherent when the 4 criteria were present (called "global adherence").Measurement unit was: Number of patients with therapeutic adherence * Morisky-Green Scale (MGLS): consists of a series of four questions with dichotomous answers (yes/no) that affect the patient's behaviour regarding compliance. * Self-reported compliance communication: Haynes-Sackett method: involves asking the patient one question. If the answer is affirmative, is considered adherent. * Records of dispensations in the pharmacy: Patients who withdrew all medications during the year were considered adherent. * Attendance at scheduled appointments: It is recorded if the patient has missed any of the control visits by both the doctor and the nurse during the first year.

    12 months after admission

Secondary Outcomes (3)

  • Rate of readmission,

    During the 12 months after the admission

  • Rate of visits to the emergency room

    During the 12 months after the admission

  • Rate of mortality

    During the 12 months after the admission

Study Arms (2)

nursing intervention group

EXPERIMENTAL

An educational interview by trained nurses was performed at three months in patients allocated to the intervention group. The visit was carried out at the hospital. Family and caregivers were also asked to attend this visit for instruction. For patients unable to move, the nursing team went to their home to perform the intervention, or it was conducted by phone. The duration of this interview was approximately 40 minutes and was focused on some measures and recommendations to improve or maintain adherence. Then, there is a reminder call at 6 months.

Other: Nursing intervention programme

Usual care group

NO INTERVENTION

The patient is followed up and regular visits

Interventions

educational information

nursing intervention group

Eligibility Criteria

Age75 Years+
Sexall
Healthy VolunteersNo
Age GroupsOlder Adult (65+)

You may qualify if:

  • Patients with STEMI aged 75 years or older underwent primary percutaneous coronary intervention (PCI)

You may not qualify if:

  • Patients who refused to participate in the study
  • Patients unable to perform geriatric assessment.
  • Patients admitted to nursing homes or social health centres.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (1)

  • Calvo E, Izquierdo S, Castillo R, Cesar E, Domene G, Gomez AB, Guerrero C, Andreu-Periz L, Gomez-Hospital JA, Ariza-Sole A. Can an individualized adherence education program delivered by nurses improve therapeutic adherence in elderly people with acute myocardial infarction?: A randomized controlled study. Int J Nurs Stud. 2021 Aug;120:103975. doi: 10.1016/j.ijnurstu.2021.103975. Epub 2021 May 10.

MeSH Terms

Conditions

Medication AdherenceMyocardial Infarction

Condition Hierarchy (Ancestors)

Patient CompliancePatient Acceptance of Health CareTreatment Adherence and ComplianceHealth BehaviorBehaviorMyocardial IschemiaHeart DiseasesCardiovascular DiseasesVascular DiseasesInfarctionIschemiaPathologic ProcessesPathological Conditions, Signs and SymptomsNecrosis

Study Officials

  • Elena Calvo, RN

    Nurse

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
TRIPLE
Who Masked
CARE PROVIDER, INVESTIGATOR, OUTCOMES ASSESSOR
Masking Details
The random assignment was made to the "nursing intervention group" and the "usual care group", generating a list using the EPIDAT ® programme. This list contained the patient number and the assignment group. The randomization procedure was performed during hospitalization for AMI. The researcher did not know the assignment list, calling the research unit at the time of each patient inclusion by phone, when they were told to which group they would belong to once the first interview was over. The main outcome measured was therapeutic adherence 12 months after admission. This assessment was performed by trained nurses blinded to the group assignment.
Purpose
PREVENTION
Intervention Model
PARALLEL
Model Details: Patients were randomly assigned to a nursing intervention group or a usual care group (1:1). Nonprobabilistic, consecutive sampling was carried out with random assignment of the study groups.
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

November 28, 2020

First Posted

December 10, 2020

Study Start

April 1, 2016

Primary Completion

February 28, 2020

Study Completion

May 28, 2020

Last Updated

December 14, 2020

Record last verified: 2020-12

Data Sharing

IPD Sharing
Will not share