Role of High Flow Nasal Oxygen as a Strategy for Weaning From Invasive Mechan

NCT04657796 | Unknown

• 1 other identifier: HFNCWEANINGMODE
• Study Type: observational
• Target: 84
• Locations: 0 countries
• Sites: N/A

Brief Summary

evaluate the Efficacy of high flow nasal oxygen as a weaning strategy in mechanically ventilated patients with respiratory failure.

Conditions

Respiratory Failure With Hypoxia

Outcome Measures

Primary Outcomes (1)

• Is patient outcome in terms of survival or death at discharge.

  evaluate the Efficacy of high flow nasal oxygen as a weaning strategy in mechanically ventilated patients with respiratory failure as regarding Hospitalization ,complications, oxygenation , reintubation rate, mortality rate.

  through study completion average 7 days.

Secondary Outcomes (1)

• Duration of ICU stay through study completion average 7 days ,Adverse events.

  through study completion average 7 days.

Interventions

High Flow Nasal Cannula DEVICE

use of high flow nasal cannula as a weaning mode from invasive mechanical ventilation to deliver oxygen

Eligibility Criteria

• Age: 18 Years - 100 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

all patient in respiratory ICU who mechanically intubated will be enrolled in study by using high flow nasal oxygen as a weaning strategy.

You may qualify if:

• All adult patients who were admitted to our ICU requiring endotracheal intubation (ETI), were eligible for the study.

You may not qualify if:

• Non-intubated patients or those with tracheostomy were excluded from the study.
• those having neurological alteration unrelated to hypercapnoeic encephalopathy, cranio-facial deformity, upper airway obstruction, cardiogenic pulmonary edema, cardiogenic shock, acute myocardial infarction, pneumothorax, pulmonary neoplasm, pulmonary thromboembolism, gastrointestinal bleeding, and post-operative respiratory failure.
• Patients less than 18 y.

Sponsors & Collaborators

• Assiut University: lead

Related Publications (3)

• Papazian L, Corley A, Hess D, Fraser JF, Frat JP, Guitton C, Jaber S, Maggiore SM, Nava S, Rello J, Ricard JD, Stephan F, Trisolini R, Azoulay E. Use of high-flow nasal cannula oxygenation in ICU adults: a narrative review. Intensive Care Med. 2016 Sep;42(9):1336-49. doi: 10.1007/s00134-016-4277-8. Epub 2016 Mar 11.

  PMID: 26969671 BACKGROUND

• Helviz Y, Einav S. A Systematic Review of the High-flow Nasal Cannula for Adult Patients. Crit Care. 2018 Mar 20;22(1):71. doi: 10.1186/s13054-018-1990-4.

  PMID: 29558988 BACKGROUND

• Drake MG. High-Flow Nasal Cannula Oxygen in Adults: An Evidence-based Assessment. Ann Am Thorac Soc. 2018 Feb;15(2):145-155. doi: 10.1513/AnnalsATS.201707-548FR.

  PMID: 29144160 RESULT

Study Officials

• Suzan Sl Sayed, Professor

  Assiut University

  STUDY DIRECTOR

Central Study Contacts

Hamed Fr Qenawy, Bachelor

CONTACT

01061812045; hamedfarrag216@gmail.com

Doaa Mo Magdy, Lecturer

CONTACT

01006261010; doaamagdy_2020@yahoo.com

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: October 4, 2020
• First Posted: December 8, 2020
• Study Start: December 5, 2020
• Primary Completion: October 5, 2022
• Study Completion: December 4, 2023
• Last Updated: December 8, 2020

Record last verified: 2020-12