Thiol/Disulfide and Oxidative Stress
Evaluation of Saliva Thiol/Disulfide Homeostasis and Oxidative Stress in Children With Severe Early Childhood Caries by a Novel Method- Part 1
1 other identifier
observational
80
1 country
1
Brief Summary
The aim of this study was to evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2020
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 10, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
June 10, 2020
CompletedStudy Completion
Last participant's last visit for all outcomes
September 15, 2020
CompletedFirst Submitted
Initial submission to the registry
November 30, 2020
CompletedFirst Posted
Study publicly available on registry
December 7, 2020
CompletedDecember 7, 2020
November 1, 2020
1 month
November 30, 2020
November 30, 2020
Conditions
Outcome Measures
Primary Outcomes (1)
thiol/disulfide homeostasis
Unstimulated saliva samples were taken from all children. Then, thiol/disulfide homeostasis and antioxidant levels were evaluated.
six months
Study Arms (2)
severe early childhood caries
healthy children
Interventions
evaluate the role of thiol/disulfide homeostasis and oxidative stress in the saliva of children with severe early childhood caries and healthy group
Eligibility Criteria
the children with severe early childhood caries which are 3-5 years
You may qualify if:
- years
You may not qualify if:
- the children with systemic illness, using anti-inflammatory drug
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Aslı Soğukpınar
Kahramanmaraş, Turkey (Türkiye)
Study Design
- Study Type
- observational
- Observational Model
- CASE CONTROL
- Time Perspective
- CROSS SECTIONAL
- Target Duration
- 6 Months
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Dr.
Study Record Dates
First Submitted
November 30, 2020
First Posted
December 7, 2020
Study Start
May 10, 2020
Primary Completion
June 10, 2020
Study Completion
September 15, 2020
Last Updated
December 7, 2020
Record last verified: 2020-11