NCT04655196

Brief Summary

In this study, people who suffer from loneliness will be randomized to three study conditions. The first and second group get an account to an internet-based self-help intervention. The first group also receives weekly feedback from a coach and the second group receives an automated email on a weekly basis. The third group is a waiting control group. In all three conditions additional care or treatment is allowed. The aim of the study is to investigate the efficacy of an internet-based self-help intervention to reduce feelings of loneliness compared to a waiting list and the effect of support during the intervention. Assessments are at baseline, 5-week, 10-week, 6-months and 12-months post-randomization. Participants in the waiting control group get also access to the intervention and fill out questionnaires at baseline, 5-week and 10-week post-randomization and get also access to the intervention 10 weeks after randomization.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
243

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started May 2021

Typical duration for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 27, 2020

Completed
10 days until next milestone

First Posted

Study publicly available on registry

December 7, 2020

Completed
5 months until next milestone

Study Start

First participant enrolled

May 17, 2021

Completed
1.5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 18, 2022

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

September 22, 2023

Completed
Last Updated

November 7, 2023

Status Verified

November 1, 2023

Enrollment Period

1.5 years

First QC Date

November 27, 2020

Last Update Submit

November 6, 2023

Conditions

Keywords

internet-based self-helploneliness

Outcome Measures

Primary Outcomes (1)

  • Loneliness

    Measured with the UCLA Loneliness Scale, 9-Item Version (UCLA-9). Total score ranging from 1-4 (representing the mean score of all 9 items). Lower scores represent less loneliness and a more favourable outcome.

    10-week

Secondary Outcomes (19)

  • Depressive Symptoms

    Baseline, 5-week, 10-week, 6-months, 12-months

  • Satisfaction with Life

    Baseline, 5-week, 10-week, 6-months, 12-months

  • Misanthropy

    Baseline, 10-week, 6-months, 12-months

  • Self-Stigma in Loneliness

    Baseline, 10-week, 6-months, 12-months

  • Social Interaction Anxiety

    Baseline, 10-week, 6-months, 12-months

  • +14 more secondary outcomes

Study Arms (3)

Internet-based self-help + weekly feedback by a coach

EXPERIMENTAL

Internet-based self-help on the basis of CBT-interventions, mindfulness and self-compassion to address cognitions, emotions and behavior related to loneliness. The self-help program consists of nine text, audio and video-based sessions, various exercises (e.g., breathing meditation, diaries) and tasks. Participants receive weekly feedback by a coach.

Other: SOLUS-D + weekly feedback by a coach

Internet-based self-help + weekly automated messages

EXPERIMENTAL

Internet-based self-help on the basis of CBT-interventions, mindfulness and self-compassion to address cognitions, emotions and behavior related to loneliness. The self-help program consists of nine text-, audio- and video-based sessions, various exercises (e.g., breathing meditation, diaries) and tasks. Participants receive weekly automated messages in order to increase motivation.

Other: SOLUS-D + weekly automated messages

Waiting control group

NO INTERVENTION

Interventions

internet-based self-help

Internet-based self-help + weekly feedback by a coach

internet-based self-help

Internet-based self-help + weekly automated messages

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Sumscore ≥ 18 on the UCLA Loneliness Scale
  • Signed Informed Consent
  • Contact information provided in case of emergency
  • Internet connection and device to use it (Smartphone, Computer, Tablet)
  • Fluent in german language

You may not qualify if:

  • Acute suicidality
  • A current diagnose of substance dependence, a current or previous diagnose of psychotic disorder or bipolar disorder
  • A current diagnosis of severe depression (PHQ-9 \> 14)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Bern

Bern, 3012, Switzerland

Location

Related Publications (2)

  • Seewer N, Skoko A, Kall A, Andersson G, Luhmann M, Berger T, Krieger T. Efficacy of an Internet-based self-help intervention with human guidance or automated messages to alleviate loneliness: a three-armed randomized controlled trial. Sci Rep. 2024 Mar 19;14(1):6569. doi: 10.1038/s41598-024-57254-0.

  • Seewer N, Skoko A, Kall A, Andersson G, Luhmann M, Berger T, Krieger T. Evaluating the Efficacy of a Guided and Unguided Internet-Based Self-help Intervention for Chronic Loneliness: Protocol for a 3-Arm Randomized Controlled Trial. JMIR Res Protoc. 2022 Jul 22;11(7):e36358. doi: 10.2196/36358.

Study Officials

  • Tobias Krieger, PD Dr.

    University of Bern

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 27, 2020

First Posted

December 7, 2020

Study Start

May 17, 2021

Primary Completion

November 18, 2022

Study Completion

September 22, 2023

Last Updated

November 7, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will share

Locations