GERAP's Epidemiological Survey on Perioperative Hypersensitivity Reactions
SERAP
Epidemiological Survey on Perioperative Hypersensitivity Reactions in France by the GERAP Network (Groupe d'étude Des réactions Anaphylactiques périopératoires)
1 other identifier
observational
3,000
1 country
1
Brief Summary
Perioperative hypersensitivity reactions are still associated with significant morbidity and mortality despite early recognition and use of epinephrine. The epidemiology of these reactions evolves over time and changes with clinical practice. The main objective is to study the epidemiology of these reactions over a 10-year period, including patient phenotype, reaction phenotype and outcome of the allergic work-up.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Nov 2020
Longer than P75 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
November 12, 2020
CompletedFirst Submitted
Initial submission to the registry
December 3, 2020
CompletedFirst Posted
Study publicly available on registry
December 4, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
May 12, 2031
ExpectedStudy Completion
Last participant's last visit for all outcomes
May 12, 2031
May 3, 2023
April 1, 2023
10.5 years
December 3, 2020
May 2, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Retrospective analysis of incidence of all perioperative hypersensitivity reactions referred in an allegro-anesthetic
Outcome is analysed every 2 years over a 10 years period
Eligibility Criteria
Subject having experienced a perioperative hypersensitivity reaction
You may qualify if:
- Minor and major subject
- Subject having experienced a perioperative hypersensitivity reaction between January the 1st 2017 and December the 31st 2027.
- Referred for an allegro-anesthetic workup
- Subject not having expressed his opposition, after information, to the reuse of his data for the purposes of this research.
You may not qualify if:
- Subject having expressed opposition to participating in the study
- Inability to provide the subject with research information
- Subject under guardianship or guardianship
- Subject under safeguard of justice
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Service d'anesthésie-réanimation - CHU de Strasbourg - France
Strasbourg, 67091, France
Related Publications (1)
Tacquard C, Serrier J, Viville S, Chiriac AM, Franchina S, Gouel-Cheron A, Giraudon A, Le Guen M, Le Quang D, Malinovsky JM, Petitpain N, Demoly P, Mertes PM; GERAP study group. Epidemiology of perioperative anaphylaxis in France in 2017-2018: the 11th GERAP survey. Br J Anaesth. 2024 Jun;132(6):1230-1237. doi: 10.1016/j.bja.2024.01.044. Epub 2024 Mar 16.
PMID: 38493055DERIVED
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- STUDY DIRECTOR
Paul-Michel MERTES, MD, PhD
Strasbourg University Hospitals - Anesthesia-intensive care unit
- PRINCIPAL INVESTIGATOR
Charles TACQUARD, MD
Strasbourg University Hospitals - Anesthesia-intensive care unit
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
December 3, 2020
First Posted
December 4, 2020
Study Start
November 12, 2020
Primary Completion (Estimated)
May 12, 2031
Study Completion (Estimated)
May 12, 2031
Last Updated
May 3, 2023
Record last verified: 2023-04