Predictive Multimodal MRI Factors in Subacute Cerebral Artery Occlusiontreated by Thrombectomy (PIMISUTT)
PIMISUTT
2 other identifiers
interventional
50
1 country
1
Brief Summary
Our study aims to measure metabolic and functional parameters of the infarcted territory by multimodal cerebral MRI in patients diagnosed with unilateral proximal occlusion of the middle cerebral artery and treated by thrombectomy in order to correlate those parameters to clinical outcome (evaluated by modified Rankin score) at 3 months. We aim to find early radiologic predictive factors for favorable clinical outcome in this population of patients.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P25-P50 for not_applicable
Started Nov 2021
Longer than P75 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
November 25, 2020
CompletedFirst Posted
Study publicly available on registry
December 3, 2020
CompletedStudy Start
First participant enrolled
November 15, 2021
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 15, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
August 15, 2025
CompletedDecember 16, 2024
December 1, 2024
3.8 years
November 25, 2020
December 11, 2024
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Correlation between modified Rankin score at 3 months and multimodal MRI data
Month 3
Secondary Outcomes (3)
Discharge National Institute of Health Stroke Score (NIHSS)
Month 3
National Institute of Health Stroke (NIHSS) score at 3 months
Month 3
Change in NIHSS score at 3 months compared to post-thrombectomy
Month 3
Study Arms (1)
Multimodal MRI
EXPERIMENTALInterventions
Multimodal MRI will be realized between 12 and 24 hours after thrombectomy
Eligibility Criteria
You may qualify if:
- Patients aged ≥ 18 years old
- Hospitalized at the Poitiers University Hospital
- Acute middle cerebral artery occlusion diagnosed by CT-scan or MRI
- NIHSS score ≥ 6 at admission
- To be treated by thrombectomy with or without fibrinolysis
- Written information delivered to the patient or his relatives concerning the study and its benefit and risk
You may not qualify if:
- Patients or relatives whom a loyal information about the study cannot be given
- Patient with cognitive impairments before MRI.
- Patients who cannot undergo MRI because of contraindications
- Patients too deteriorated to tolerate one hour long exam
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
CHU Poitiers
Poitiers, France
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Central Study Contacts
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- NA
- Masking
- NONE
- Purpose
- PREVENTION
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
November 25, 2020
First Posted
December 3, 2020
Study Start
November 15, 2021
Primary Completion
August 15, 2025
Study Completion
August 15, 2025
Last Updated
December 16, 2024
Record last verified: 2024-12