Police COVID-19 Serosurvey

NCT04643444 | Completed DMC

• 1 other identifier: 2020-02650
• Study Type: observational
• Target: 1,024
• Locations: 1 country
• Sites: 1

Brief Summary

The investigators aim to determine the immune status of the employees of the cantonal police of Bern against SARS-CoV-2 over a period of 1 year, and to investigate the risk profile of the study participants and their risk of SARS-CoV-2 exposure in their working and private environments, as well as to evaluate the use of personal protective equipment at potential exposure instances.

Conditions

SARS-CoV-2 Infection; Volunteers; Healthy

Keywords

COVID-19; SARS-COV-2; Antibodies; Seroprevalence

Outcome Measures

Primary Outcomes (1)

• Seroprevalence

  The variable of primary interest is COVID-19 seropositivity. This variable is measured at five time points over the one-year study period. The following baseline factors may have an influence on the primary endpoint and will be obtained: (i) pre-existing comorbidities, (ii) rural versus city distribution of working place, and (iii) office work versus field work.

  One year

Secondary Outcomes (1)

• Risk profile assessment

  One year

Interventions

Blood sampling DIAGNOSTIC_TEST

Testing for the presence of SARS-CoV-2 antibodies

Online Questionnaire OTHER

Questions on working place, risk profiles and PPE

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Employees of the cantonal police of Bern, Switzerland

You may qualify if:

• Police officers of the cantonal police of Bern volunteering to participate in the study.

You may not qualify if:

• Refusal or inability to give informed consent or contraindication to venepuncture.

Sponsors & Collaborators

• University of Bern: lead
• Interregionale Blutspende SRK Bern: collaborator

Study Sites (1)

University of Bern, Institute for Infectious Diseases

Bern, Canton of Bern, 3010, Switzerland

Location

Related Publications (1)

• Sendi P, Baldan R, Thierstein M, Widmer N, Gowland P, Gahl B, Buchi AE, Guntensperger D, Wider M, Blum MR, Tinguely C, Maillat C, Theel ES, Berbari E, Dijkman R, Niederhauser C. A Multidimensional Cross-Sectional Analysis of Coronavirus Disease 2019 Seroprevalence Among a Police Officer Cohort: The PoliCOV-19 Study. Open Forum Infect Dis. 2021 Oct 16;8(12):ofab524. doi: 10.1093/ofid/ofab524. eCollection 2021 Dec.

  PMID: 34888394 DERIVED

Biospecimen

Retention: SAMPLES WITHOUT DNA

Serum

MeSH Terms

Conditions

COVID-19

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Officials

• Parham Sendi, MD

  University of Bern

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 19, 2020
• First Posted: November 25, 2020
• Study Start: February 9, 2021
• Primary Completion: June 30, 2022
• Study Completion: June 30, 2022
• Last Updated: November 21, 2025

Record last verified: 2025-11

Data Sharing

• IPD Sharing: Will not share

Locations

CH (1)