Physiotherapy Applications in Upper Extremity Lipedema

NCT04643392 | Completed

• 1 other identifier: YIU
• Study Type: observational
• Target: 14
• Locations: 1 country
• Sites: 1

Brief Summary

Lipedema which causes excessive accumulation of fat in the subcutaneous tissue, is a rare, progressive disease. This disease generally affects women, following puberty or early adulthood and usually results in the slow increase of the circumference of the legs and/or arms, bilaterally. In a typical presentation of lipedema, the enlargement of the lower extremities is disproportionately greater than that of the trunk and upper extremities When first described in 1940, lipedema was thought to exclusively affect the lower extremities. However, as the disease has been recognized over the years, lipedema has been reported to affect the upper extremities. Upper extremity lipedema, with no involvement of the lower extremities is an extremely rare incident.

Conditions

Lipedema

Keywords

Upper extremity lipedema; Lymphatic drainage

Outcome Measures

Primary Outcomes (2)

• Limb Circumference

  For every patient, the circumference measurements of the upper limbs were measured with the Perometer.

  Change from baseline circumference at 4 weeks

• Limb Volume

  For every patient, the volume measurements of the upper limbs were measured with the Perometer.

  Change from baseline volume at 4 weeks

Study Arms (1)

Patients with Lipedema

Participants who were diagnosed with upper extremity lipedema by a lymphologist.

Procedure: Complex decongestive physiotherapy

Interventions

Complex decongestive physiotherapy PROCEDURE

Each patient received a treatment protocol of Complex decongestive physiotherapy for 5 days a week until they were discharged from the clinic. All patients fully completed all components of the treatment routine daily. The treatment was performed by a physiotherapist who was certified with Manual Lymph Drainage Combined Decongestive Physiotherapy. After the daily treatment protocol was completed, patients wore standard or individually sized compression grade II or III medical compression stockings for the rest of the day.

Patients with Lipedema

Eligibility Criteria

• Age: 18 Years - 65 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients between the age of 18-65 who have lipedema affecting the upper extremities and no accompanying diagnosis of lymphedema, deep vein thrombosis or any disease which causes edema in the upper extremities.

You may qualify if:

• being between the ages of 18-65,
• having a diagnosis of upper extremity lipedema
• being willing to participate in the study

You may not qualify if:

• accompanying diagnosis of lymphedema,
• deep vein thrombosis
• disease which causes edema in the upper extremities

Sponsors & Collaborators

• Yuksek Ihtisas University: lead

Study Sites (1)

Yuksek Ihtisas University

Ankara, 06560, Turkey (Türkiye)

Location

Related Publications (1)

• Volkan-Yazici M, Esmer M. Reducing Circumference and Volume in Upper Extremity Lipedema: The Role of Complex Decongestive Physiotherapy. Lymphat Res Biol. 2022 Feb;20(1):71-75. doi: 10.1089/lrb.2020.0128. Epub 2021 Apr 5.

  PMID: 33798399 DERIVED

MeSH Terms

Conditions

Lipedema

Condition Hierarchy (Ancestors)

Connective Tissue Diseases; Skin and Connective Tissue Diseases

Study Officials

• Melek Volkan-Yazici, PT. PhD

  Yuksek Ihtisas University

  PRINCIPAL INVESTIGATOR

• Murat Esmer, PT. MSc

  Gazi University

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 4 Weeks
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: November 18, 2020
• First Posted: November 25, 2020
• Study Start: September 2, 2019
• Primary Completion: February 3, 2020
• Study Completion: May 4, 2020
• Last Updated: November 25, 2020

Record last verified: 2020-11

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)