NCT04643015

Brief Summary

This study is being done to see how we can prevent problems caused by movement during the MRI scan. Different ways of doing the scan (techniques) will be tested to see if they are practical and can prevent problems related to motion. For example, changes in the timing of the magnetic field and the radio waves will be examined, and at changes in the way a computer is used to process the images. The new techniques will be compared with the techniques that are usually used.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for all trials

Timeline
6mo left

Started Nov 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress91%
Nov 2020Nov 2026

Study Start

First participant enrolled

November 18, 2020

Completed
1 day until next milestone

First Submitted

Initial submission to the registry

November 19, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

November 24, 2020

Completed
6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 18, 2026

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 18, 2026

Last Updated

September 3, 2025

Status Verified

August 1, 2025

Enrollment Period

6 years

First QC Date

November 19, 2020

Last Update Submit

August 26, 2025

Conditions

Pediatric DisorderAdult Disease

Keywords

Magnetic Resonance ImagingMRI20-482Memorial Sloan Kettering Cancer Center

Outcome Measures

Primary Outcomes (1)

  • Compare Image Quality

    To assess the new MRI sequences or MRI analysis methods and compare their image quality to current clinical ones. Specifically, we aim to compare the routine sequences with the experimental sequences.

    Day of MRI

Study Arms (1)

Study Participants

Patients of any age, including males and females, who are being treated in the Department of Pediatrics and are already scheduled to undergo MRI

Diagnostic Test: MRI

Interventions

MRIDIAGNOSTIC_TEST

Briefly, new MRI sequences will be used on a patient who is undergoing a scheduled, clinically necessary MRI exam. Any new research sequence will be scanned in addition to the clinically required sequences and will not interfere with the clinical scan other than requiring five to ten minutes of additional "table time". There will be no invasive measures under this protocol.

Study Participants

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Potential research subjects will be identified by a member of the patient's treatment team, the protocol investigator, or research team at Memorial Sloan-Kettering Cancer Center (MSK). With consultation of the clinical team, the investigator or a consenting professional from the research team will go to the treating physician's clinic to discuss the study and consent the patient in person.

You may qualify if:

  • Patients of any age, including males and females, who are being treated in the Department of Pediatrics and are already scheduled to undergo MRI

You may not qualify if:

  • Anyone who would normally be excluded from undergoing an MRI examination as per Memorial Hospital for Cancer and Allied Diseases Screening Questionnaire for MRI (Appendix A). Subjects with pacemakers or aneurysm clips that are MRI conditional or MRI compatible may enroll in the study if the study is clinically indicated.
  • Female patients who are pregnant
  • Patients who are unable to comply or complete the MRI exam due to claustrophobia or high levels of anxiety
  • Patients at higher risk due to age, frailty, or the emergent nature of their condition
  • Patients who are undergoing MRI only of the head, neck or spine

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Memorial Sloan Kettering Cancer Center

New York, New York, 10065, United States

Location

Related Links

MeSH Terms

Conditions

Disease

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Study Officials

  • Gerald Behr, MD

    Memorial Sloan Kettering Cancer Center

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 19, 2020

First Posted

November 24, 2020

Study Start

November 18, 2020

Primary Completion (Estimated)

November 18, 2026

Study Completion (Estimated)

November 18, 2026

Last Updated

September 3, 2025

Record last verified: 2025-08

Data Sharing

IPD Sharing
Will share

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

Locations

US(1)