NCT04640064

Brief Summary

A multicenter retrospective observational study among children with type 1 diabetes will be performed. The Objective of this study will be to determine a) the association between the increase in Hba1c in children with type 1 diabetes and confinement due to the COVID 19 pandemic. b) the association between the frequency of patient care during social confinement and the Hba1c values. Different centers from Latin America including Argentina, Peru, Panama, Chile, and Ecuador will participate in this study. Children younger than 17 years with a diagnosis of type 1 diabetes prior to 2018 will be included. Data from the medical records of the participating centers will be collected on the Hb A1c value before and after confinement (6 months completed). The initial (base) value will be taken as a value of HbA1c registered in the patient's Clinical History for the year 2018, 2019, and 2020 pre and post quarantine (Sep-Oct-Nov) 2020, considering compliance with six months of quarantine. Hb A1c should have been performed in the same institution or with the same methods in order to avoid bias.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
500

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Nov 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 17, 2020

Completed
5 days until next milestone

Study Start

First participant enrolled

November 22, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

November 23, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 22, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 22, 2021

Completed
Last Updated

November 23, 2020

Status Verified

November 1, 2020

Enrollment Period

4 months

First QC Date

November 17, 2020

Last Update Submit

November 17, 2020

Conditions

Keywords

Type 1 diabetes, children, pandemic, HBA1c,

Outcome Measures

Primary Outcomes (1)

  • Hb A1C pre and post Confinement in Latin American children with Type 1 Diabetes

    The increase in Hba1c in children with type 1 diabetes and confinement due to the COVID 19 pandemic

    six months

Study Arms (1)

Patient with type 1 diabetes

Children younger than 17 years with a diagnosis of type 1 diabetes prior to 2018 will be included.

Eligibility Criteria

Age2 Years - 17 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

A multicenter retrospective observational study among children with type 1 diabetes will be performed. Different centers from Latin America including Argentina, Peru, Panama, Chile, and Ecuador will participate in this study. Children younger than 17 years with a diagnosis of type 1 diabetes prior to 2018 will be included. Data from the medical records of the participating centers will be collected on the Hb A1c value before and after confinement (6 months completed). The initial (base) value will be taken as a value of HbA1c registered in the patient's Clinical History for the year 2018, 2019, and 2020 pre and post quarantine (Sep-Oct-Nov) 2020, considering compliance with six months of quarantine. Hb A1c should have been performed in the same institution or with the same methods in order to avoid bias.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Valeria Hirschler

Buenos Aires, 1006, Argentina

Location

MeSH Terms

Conditions

Precursor Cell Lymphoblastic Leukemia-LymphomaDiabetes Mellitus, Type 1

Condition Hierarchy (Ancestors)

Leukemia, LymphoidLeukemiaNeoplasms by Histologic TypeNeoplasmsHematologic DiseasesHemic and Lymphatic DiseasesLymphoproliferative DisordersLymphatic DiseasesImmunoproliferative DisordersImmune System DiseasesDiabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System DiseasesAutoimmune Diseases

Study Design

Study Type
observational
Observational Model
CASE CROSSOVER
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER GOV
Responsible Party
SPONSOR

Study Record Dates

First Submitted

November 17, 2020

First Posted

November 23, 2020

Study Start

November 22, 2020

Primary Completion

March 22, 2021

Study Completion

April 22, 2021

Last Updated

November 23, 2020

Record last verified: 2020-11

Locations