NCT04637646

Brief Summary

This study aims to evaluate the different cardiac changes in the various types of MPS disorder and define the outcome of these cardiac abnormalities in those patients admitted to assuit University Children Hospital

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
25

participants targeted

Target at below P25 for all trials

Timeline
Completed

Started Dec 2020

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

November 16, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

November 20, 2020

Completed
11 days until next milestone

Study Start

First participant enrolled

December 1, 2020

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 29, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

January 29, 2022

Completed
Last Updated

November 20, 2020

Status Verified

November 1, 2020

Enrollment Period

1.1 years

First QC Date

November 16, 2020

Last Update Submit

November 16, 2020

Conditions

Mucopolysaccharidoses

Outcome Measures

Primary Outcomes (1)

  • Rate of Cardiac affection in patients with MPS

    cardiac affection in MPS patients

    on enrollment

Study Arms (1)

children with MPS

Eligibility Criteria

Age1 Day - 18 Years
Sexall
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

patients with mucopolysacchridosis

You may qualify if:

  • \- All the patients at any age up to 18 years with any type of MPS confirmed by the enzymatic assay

You may not qualify if:

  • any patient other than MPS

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Mucopolysaccharidoses

Condition Hierarchy (Ancestors)

Carbohydrate Metabolism, Inborn ErrorsMetabolism, Inborn ErrorsGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesLysosomal Storage DiseasesMucinosesConnective Tissue DiseasesSkin and Connective Tissue DiseasesMetabolic DiseasesNutritional and Metabolic Diseases

Central Study Contacts

hager mohamed rageh, MBChB

CONTACT

01065007569hagerdardiry@gmail.com

Mohamed Mahrous Sayed El-Talawy, PhD

CONTACT

01003486596ohamed.mohamed51@med.au.edu.eg

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
researcher

Study Record Dates

First Submitted

November 16, 2020

First Posted

November 20, 2020

Study Start

December 1, 2020

Primary Completion

December 29, 2021

Study Completion

January 29, 2022

Last Updated

November 20, 2020

Record last verified: 2020-11