Ideation Trajectories and Suicide Attempts in Adolescents With Psychiatric Disorders in Chile

NCT04635163 | Completed

• 1 other identifier: University Catholic of Maule
• Study Type: observational
• Target: 388
• Locations: 1 country
• Sites: 1

Brief Summary

This project seeks to evaluate the trajectories of suicidal ideation and attempts in adolescent patients with psychiatric disorders in secondary care controls in the Maule region, in relation to clinical factors (depressive symptoms, anxiety, stress, psychiatric comorbidity, mistreatment or abuse, history of psychiatric disorders and pharmacological treatments); psychological (parenting styles, impulsivity, barriers in seeking help and emotional regulation), and neuropsychological (executive function-decision making).

Conditions

Mental Disorders; Suicide, Attempted

Keywords

Suicidal behavior; Psychiatric disorders; Adolescents

Outcome Measures

Primary Outcomes (4)

• High levels of suicidal ideation and likelihood of suicide attempts during the follow-up period

  High levels of suicidal ideation at first measurement, predicts a higher likelihood of suicide attempts during the follow-up period.

  3 years

• Suicidal ideation and previous attempts versus single attempt

  Adolescents with suicidal ideation and previous attempts will be more likely to repeat than those with a single attempt.

  3 years

• Clinical and psychological factors, predispose irregular course of suicidal thoughts and scant seek for help.

  Adolescents with less emotional regulation, poor parenting styles, high levels of impulsivity and a history of self-harm will have significant differences in levels of suicidal ideation during the follow-up period (3 measurements) and more than 60% of them will report that they do not seek help to deal with your mental health problems.

  3 years

• Severity of suicidal ideation according to psychiatric comorbidity, impaired decision-making capacity, and previous suicide attempts.

  Adolescents with previous suicide attempts, psychiatric comorbidity, and impaired decision-making capacity, have a greater severity of suicidal ideas, and consequently, are more likely to repeat a suicide attempt than those without these characteristics.

  3 years

Interventions

None intervention OTHER

None intervention

Eligibility Criteria

• Age: 15 Years - 19 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Adolescents of both genders will be selected utilizing a non-probability purposive sampling, ranging from 15 to 19 years of age and diagnosed with a psychiatric disorder with or without ideation and suicidal attempts, being under treatment in Mental Health units in hospitals and Health Centers in the Maule Region, with capacity for reading and writing, and not presenting an disabling medical illness and/or active psychotic symptomatology.

You may qualify if:

• Adolescents between 15 and 19 years old
• Diagnosed with psychiatric disorder
• With and without suicidal ideation
• With and without suicide attempts
• With the ability to read and write
• Those who give their assent, in addition to an informed consent signed by their mother and / or father or legal representative

You may not qualify if:

• Adolescents who do not have the ability to read and / or write.
• Those who refuse to participate in the study, whose mother and / or father or legal representative do not give their consent
• Suffering from a disabling medical illness and / or active psychotic symptoms

Sponsors & Collaborators

• Universidad Católica del Maule: lead
• Fondo Nacional de Desarrollo Científico y Tecnológico, Chile: collaborator

Study Sites (1)

University Catholic Maule. Chile

Talca, 3460000, Chile

Location

Related Publications (12)

• Wasserman D, Rihmer Z, Rujescu D, Sarchiapone M, Sokolowski M, Titelman D, Zalsman G, Zemishlany Z, Carli V; European Psychiatric Association. The European Psychiatric Association (EPA) guidance on suicide treatment and prevention. Eur Psychiatry. 2012 Feb;27(2):129-41. doi: 10.1016/j.eurpsy.2011.06.003. Epub 2011 Dec 1.

  PMID: 22137775 BACKGROUND

• Miranda R, Shaffer D. Understanding the suicidal moment in adolescence. Ann N Y Acad Sci. 2013 Nov;1304:14-21. doi: 10.1111/nyas.12291. Epub 2013 Oct 18.

  PMID: 24138124 BACKGROUND

• Schrijvers DL, Bollen J, Sabbe BG. The gender paradox in suicidal behavior and its impact on the suicidal process. J Affect Disord. 2012 Apr;138(1-2):19-26. doi: 10.1016/j.jad.2011.03.050. Epub 2011 May 6.

  PMID: 21529962 BACKGROUND

• Bachmann S. Epidemiology of Suicide and the Psychiatric Perspective. Int J Environ Res Public Health. 2018 Jul 6;15(7):1425. doi: 10.3390/ijerph15071425.

  PMID: 29986446 RESULT

• Shain B; COMMITTEE ON ADOLESCENCE. Suicide and Suicide Attempts in Adolescents. Pediatrics. 2016 Jul;138(1):e20161420. doi: 10.1542/peds.2016-1420.

  PMID: 27354459 RESULT

• Roh BR, Jung EH, Hong HJ. A Comparative Study of Suicide Rates among 10-19-Year-Olds in 29 OECD Countries. Psychiatry Investig. 2018 Apr;15(4):376-383. doi: 10.30773/pi.2017.08.02. Epub 2018 Feb 28.

  PMID: 29486551 RESULT

• Breton JJ, Tousignant M, Bergeron L, Berthiaume C. Informant-specific correlates of suicidal behavior in a community survey of 12- to 14-year-olds. J Am Acad Child Adolesc Psychiatry. 2002 Jun;41(6):723-30. doi: 10.1097/00004583-200206000-00012.

  PMID: 12049447 RESULT

• Nock MK, Green JG, Hwang I, McLaughlin KA, Sampson NA, Zaslavsky AM, Kessler RC. Prevalence, correlates, and treatment of lifetime suicidal behavior among adolescents: results from the National Comorbidity Survey Replication Adolescent Supplement. JAMA Psychiatry. 2013 Mar;70(3):300-10. doi: 10.1001/2013.jamapsychiatry.55.

  PMID: 23303463 RESULT

• McLoughlin AB, Gould MS, Malone KM. Global trends in teenage suicide: 2003-2014. QJM. 2015 Oct;108(10):765-80. doi: 10.1093/qjmed/hcv026. Epub 2015 Jan 31.

  PMID: 25638789 RESULT

• Miranda R, De Jaegere E, Restifo K, Shaffer D. Longitudinal follow-up study of adolescents who report a suicide attempt: aspects of suicidal behavior that increase risk of a future attempt. Depress Anxiety. 2014 Jan;31(1):19-26. doi: 10.1002/da.22194. Epub 2013 Sep 18.

  PMID: 24105789 RESULT

• Annor FB, Clayton HB, Gilbert LK, Ivey-Stephenson AZ, Irving SM, David-Ferdon C, Kann LK. Sexual Orientation Discordance and Nonfatal Suicidal Behaviors in U.S. High School Students. Am J Prev Med. 2018 Apr;54(4):530-538. doi: 10.1016/j.amepre.2018.01.013. Epub 2018 Feb 21.

  PMID: 29449136 RESULT

• Mendez-Bustos P, Fuster-Villaseca J, Lopez-Castroman J, Jimenez-Solomon O, Olivari C, Baca-Garcia E. Longitudinal trajectories of suicidal ideation and attempts in adolescents with psychiatric disorders in Chile: study protocol. BMJ Open. 2022 Feb 22;12(2):e051749. doi: 10.1136/bmjopen-2021-051749.

  PMID: 35193905 DERIVED

Related Links

• Suicidal behavior in children and adolescents: Epidemiology and risk factors
• Suicide, Keys facts
• Programa nacional de prevención del suicidio: orientaciones para su implementación
• Epidemiology of Suicidal and Risk-Taking Behavior
• Intento de suicidio y factores de riesgo en una muestra de adolescentes escolarizados de Chile
• Estrategia Nacional de Salud para el cumplimiento de los objetivos sanitarios de la década 2011-2020

MeSH Terms

Conditions

Mental Disorders; Suicide, Attempted

Condition Hierarchy (Ancestors)

Suicide; Self-Injurious Behavior; Behavioral Symptoms; Behavior

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 22, 2020
• First Posted: November 18, 2020
• Study Start: March 19, 2018
• Primary Completion: January 26, 2019
• Study Completion: December 31, 2021
• Last Updated: May 18, 2022

Record last verified: 2022-05

Data Sharing

• IPD Sharing: Will not share

Locations

CL (1)