Observational Study to Compare Outcomes of Different Psychiatric Treatment of Suicidal Adolescents

NCT04625686 | Completed Results DMC

• 1 other identifier: 2020-0686
• Study Type: observational
• Target: 249
• Locations: 1 country
• Sites: 4

Brief Summary

To address the unmet need of optimizing the treatment and management for adolescent suicidality, the investigators propose to evaluate the effectiveness and safety of telehealth services compared to inpatient and OCIC for suicidal adolescents in target population. To achieve this goal, the investigators propose a multi- site study to compare telehealth, OCIC, and inpatient care, and see which can lead to a lower risk of a suicidal event (primary outcome) as well as higher treatment satisfaction (TS) and satisfaction with life (SL) (secondary outcomes) of both the legal guardians/parents and patients.

Conditions

Suicidal Ideation

Outcome Measures

Primary Outcomes (1)

• Number of Recurrent Suicidal Events Measured by Treatment Arm

  Compare the number of recurrent suicidal event across three treatment groups. Suicidal events were measured by hospitalizations during the study time frame in analysis.

  6 Months

Secondary Outcomes (1)

• Which Treatment Leads to Better Life Satisfaction

  6 Months

Other Outcomes (1)

• Treatment Satisfaction Scores Measured by Treatment Arm

  2 weeks

Study Arms (4)

Inpatient Treatment

Inpatient psychiatric treatment

Behavioral: Mental Health Treatment

OCIC Treatment

In-person outpatient crisis intervention

Behavioral: Mental Health Treatment

Telehealth Therapy Treatment

Virtual outpatient therapy

Behavioral: Mental Health Treatment

No Show Group

Participant who do not attend recommended treatment

Interventions

Mental Health Treatment BEHAVIORAL

Treatment of suicidal ideation

Inpatient Treatment; OCIC Treatment; Telehealth Therapy Treatment

Eligibility Criteria

• Age: 12 Years - 18 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

Adolescents experiencing suicidal ideation and require a higher level of care.

You may qualify if:

• Adolescents that are 12 through 18 years old.
• Adolescents that are brought to the Emergency Department for crisis evaluation due to suicidal thoughts or behaviors.
• Require a higher level of care.
• The presence of a legal guardian for consent.
• Capable of giving signed informed consent/assent, which includes compliance with the requirements and restrictions listed in the informed consent form (ICF) and in this protocol.

You may not qualify if:

• Adolescents with suicidal thoughts who had prior OCIC treatment in the past 12 months.
• Adolescents without the ability to answer survey questions.
• Adolescents that are non-English speaking due to the scales and surveys that are used for this study only being available in English.

Sponsors & Collaborators

• Children's Hospital Medical Center, Cincinnati: lead
• Patient-Centered Outcomes Research Institute: collaborator

Study Sites (4)

Northwell Health

Queens, New York, 11004, United States

Location

Cincinnati Children's Hospital Medical Center

Cincinnati, Ohio, 45229, United States

Location

Nationwide Children's Hospital

Columbus, Ohio, 43205, United States

Location

UT Southwestern Medical Center

Dallas, Texas, 75390, United States

Location

Related Publications (4)

• Curtin SC, Warner M, Hedegaard H. Increase in Suicide in the United States, 1999-2014. NCHS Data Brief. 2016 Apr;(241):1-8.

  PMID: 27111185 BACKGROUND

• QuickStats: Suicide Rates*,dagger for Teens Aged 15-19 Years, by Sex - United States, 1975-2015. MMWR Morb Mortal Wkly Rep. 2017 Aug 4;66(30):816. doi: 10.15585/mmwr.mm6630a6. No abstract available.

  PMID: 28771461 BACKGROUND

• Green J, Jacobs B, Beecham J, Dunn G, Kroll L, Tobias C, Briskman J. Inpatient treatment in child and adolescent psychiatry--a prospective study of health gain and costs. J Child Psychol Psychiatry. 2007 Dec;48(12):1259-67. doi: 10.1111/j.1469-7610.2007.01802.x.

  PMID: 18093032 BACKGROUND

• Combs J, Lin PI, DelBello MP, Carle AC, Bridge JA, Axelson DA, Fornari V, Feuer V, Emslie GJ, Kennard BD, Porter SC, Sorter MT, Barzman D. Examining Alternative Treatment Settings for Adolescents With Suicidal Thoughts During the COVID-19 Pandemic. JAACAP Open. 2024 Nov 8;3(3):567-575. doi: 10.1016/j.jaacop.2024.10.005. eCollection 2025 Sep.

  PMID: 40922794 DERIVED

MeSH Terms

Conditions

Suicidal Ideation

Condition Hierarchy (Ancestors)

Suicide; Self-Injurious Behavior; Behavioral Symptoms; Behavior

Limitations and Caveats

This study is an observational study, which is limited in comparison to an interventional study.

Results Point of Contact

• Title: Rosalie Hemphill LSW
• Organization: Cincinnati Children's Hospital Medical Center

rosalie.hemphill@cchmc.org

5044940883

Publication Agreements

• PI is Sponsor Employee: No
• Restrictive Agreement: No

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: November 6, 2020
• First Posted: November 12, 2020
• Study Start: October 1, 2020
• Primary Completion: December 15, 2021
• Study Completion: December 15, 2021
• Last Updated: January 27, 2025
• Results First Posted: January 27, 2025

Record last verified: 2024-08

Data Sharing

• IPD Sharing: Will not share

Locations

US (4)