NCT04623125

Brief Summary

Spaced Repetition training has been found to be more effective than massed repetition for individuals with aphasia. This study seeks to examine the relative efficiency of three kinds of spacing for picture-naming training: traditional random presentation, non-adaptive spaced repetition, and adaptive spaced repetition.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
21

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2020

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2020

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

October 29, 2020

Completed
12 days until next milestone

First Posted

Study publicly available on registry

November 10, 2020

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 1, 2022

Completed
Last Updated

March 29, 2023

Status Verified

March 1, 2023

Enrollment Period

1.3 years

First QC Date

October 29, 2020

Last Update Submit

March 27, 2023

Conditions

Aphasia, AcquiredAphasia Primary Progressive

Keywords

Adaptive Spaced-RetrievalAphasiaAnomiaAnki

Outcome Measures

Primary Outcomes (1)

  • Change in Picture Naming performance across conditions

    Word retention assessed after treatment

    Change from baseline to post-intervention immediately after two weeks of daily sessions, and one month followup.

Study Arms (1)

Spaced Repetition

EXPERIMENTAL

Two weeks (10 sessions) of online picture-naming training with 60 words.

Behavioral: Spaced Retrieval Practice

Interventions

Spaced Retrieval PracticeBEHAVIORAL

Online picture-naming training with 60 words which the participant experiences word-retrieval difficulties. Cards are shuffled arranged by the computerized training program.

Spaced Repetition

Eligibility Criteria

Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • presence of a post-stroke word finding deficit (i.e. aphasia), or primary progressive aphasia.
  • ability to evaluate the correctness of one's own responses when subsequently provided the with the correct answer

You may not qualify if:

  • diagnosis of a neurological disorder other than post-stroke or primary progressive aphasia
  • inability to evaluate the correctness of ones responses when subsequently provided with the correct answer

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Baycrest Health Sciences

Toronto, Ontario, M6A 2E1, Canada

Location

MeSH Terms

Conditions

AphasiaPick Disease of the BrainAnomia

Condition Hierarchy (Ancestors)

Speech DisordersLanguage DisordersCommunication DisordersNeurobehavioral ManifestationsNeurologic ManifestationsNervous System DiseasesSigns and SymptomsPathological Conditions, Signs and SymptomsFrontotemporal DementiaFrontotemporal Lobar DegenerationDementiaBrain DiseasesCentral Nervous System DiseasesNeurocognitive DisordersMental Disorders

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Senior Scientist

Study Record Dates

First Submitted

October 29, 2020

First Posted

November 10, 2020

Study Start

October 1, 2020

Primary Completion

January 1, 2022

Study Completion

January 1, 2022

Last Updated

March 29, 2023

Record last verified: 2023-03

Locations

CA(1)