IJV Sonogram VS Cardiometry in Fluid Responsiveness In CABG

NCT04618419 | Completed

• 1 other identifier: IJVDI and fluid responsiveness
• Study Type: observational
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

The primary aim of the study is to assess the reliability of predicting fluid responsiveness in adults undergoing coronary artery bypass graft surgery using sonogram of the internal jugular vein for assessment of vessel distensibility in relation to stroke volume variation (SVV) measaured by electrical cardiometry. The secondary aim is to evaluate the ability of thoracic fluid content (TFC) measured by electrical cardiometry to be an additive value for the assessment of fluid responsiveness.

Conditions

Ultrasound of IJV; Electrical Cardiometry

Keywords

CABG surgery; Internal jugular vein; stroke volume variation; TFC

Outcome Measures

Primary Outcomes (1)

• fluid responsiveness after fluid challenge

  Correlation between SVV and IJVDI

  24 hours from the start of surgery

Interventions

internal jugular vein distensibility index DIAGNOSTIC_TEST

It is a prospective observational clinical study to correlate hemodynamic monitoring between Electrical Cardiometry and internal jugular vein distensibility index by sonogram

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Demographic data, hemodynamic parameters as heart rate (HR), and mean arterial blood pressure (MAP),CVP and urine output have been registered. Cardiac data derived from electrical cardiometry including: CO ,cardiac index( CI), stroke volume variation( SVV) and thoracic fluid content were also recorded. IJVDI by sonogram was assessed

You may qualify if:

• Adults (\>18 years old) Able to provide advanced informed consent Planned for elective CABG surgery

You may not qualify if:

• Age \< 18 years
• Severely reduced preoperative left ventricular ejection fraction \< 40 %
• Significant cardiac arrhythmia.
• Significant valvular heart disease.
• Clinically evident pulmonary disease.
• Bilaterally inserted venous catheters (jugular or subclavian vein)
• History of radiotherapy or surgery of the neck region.
• Inability to obtain interpretable ultrasound images due to a difficult acoustic window.

Sponsors & Collaborators

• Ahmed Abd El-Rahim Abd El-Hamid Hammad: lead

Study Sites (1)

Alexandria university

Alexandria, Egypt

Location

Related Publications (2)

• Aronson S, Nisbet P, Bunke M. Fluid resuscitation practices in cardiac surgery patients in the USA: a survey of health care providers. Perioper Med (Lond). 2017 Oct 19;6:15. doi: 10.1186/s13741-017-0071-6. eCollection 2017.

  PMID: 29075482 BACKGROUND

• Ma GG, Hao GW, Yang XM, Zhu DM, Liu L, Liu H, Tu GW, Luo Z. Internal jugular vein variability predicts fluid responsiveness in cardiac surgical patients with mechanical ventilation. Ann Intensive Care. 2018 Jan 16;8(1):6. doi: 10.1186/s13613-017-0347-5.

  PMID: 29340792 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Residentat department of anaesthesia and surgical intensive Care

Study Record Dates

• First Submitted: October 20, 2020
• First Posted: November 6, 2020
• Study Start: May 10, 2019
• Primary Completion: December 25, 2019
• Study Completion: January 5, 2020
• Last Updated: November 6, 2020

Record last verified: 2020-11

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)