NCT04616508

Brief Summary

This study aims to better understand how people with Parkinson's control reaching movements. Specifically, we are asking how these individuals respond to different environmental perturbations. Testing includes reaching movements made within a virtual reality set-up.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for not_applicable

Timeline
7mo left

Started Dec 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress93%
Dec 2018Dec 2026

Study Start

First participant enrolled

December 12, 2018

Completed
1.9 years until next milestone

First Submitted

Initial submission to the registry

October 23, 2020

Completed
13 days until next milestone

First Posted

Study publicly available on registry

November 5, 2020

Completed
4.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 12, 2024

Completed
2 years until next milestone

Study Completion

Last participant's last visit for all outcomes

December 12, 2026

Expected
Last Updated

November 5, 2020

Status Verified

October 1, 2020

Enrollment Period

6 years

First QC Date

October 23, 2020

Last Update Submit

October 30, 2020

Conditions

Motor ControlParkinson Disease

Keywords

motor controlParkinson diseasemotor learning

Outcome Measures

Primary Outcomes (3)

  • End-point errors

    Euclidean distance from target to final hand position (units: cm); measurement derived from position data sampled at 1000 Hz

    during intervention

  • Reaction times

    Time from visual target presentation to movement onset (units: ms); measurement derived from position data sampled at 1000 Hz

    during intervention

  • Movement times

    Time from movement onset to movement end (units: ms); measurement derived from position data sampled at 1000 Hz

    during intervention

Study Arms (1)

Behavioral testing

EXPERIMENTAL
Behavioral: motor control assessment

Interventions

motor control assessmentBEHAVIORAL

Basic science study of control of reaching movements

Behavioral testing

Eligibility Criteria

Age18 Years - 85 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Age 18-85 years
  • Able to perform reaching movements of \~20 cm (8 inches)
  • MMSE score ≥ 26/30
  • Willing and able to attend all testing sessions
  • Diagnosis of idiopathic Parkinson's disease per self report
  • Currently taking dopaminergic/dopamine agonist medication

You may not qualify if:

  • Any chronic or recent upper extremity musculoskeletal conditions that affects reaching
  • Any neurological disorders other than Parkinson's disease (e.g., seizure disorders, closed head injuries with loss of consciousness greater than 15 minutes, CNS neoplasm, history of stroke)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University of Delaware

Newark, Delaware, 19713, United States

RECRUITING

MeSH Terms

Conditions

Parkinson Disease

Condition Hierarchy (Ancestors)

Parkinsonian DisordersBasal Ganglia DiseasesBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesMovement DisordersSynucleinopathiesNeurodegenerative Diseases

Study Officials

  • Hyosub Kim, PhD

    University of Delaware

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Hyosub Kim, PhD

CONTACT

302-831-4263hyosub@udel.edu

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
BASIC SCIENCE
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 23, 2020

First Posted

November 5, 2020

Study Start

December 12, 2018

Primary Completion

December 12, 2024

Study Completion (Estimated)

December 12, 2026

Last Updated

November 5, 2020

Record last verified: 2020-10

Locations

US(1)