NCT04616053

Brief Summary

Introduction : The prevalence of type 2 diabetes is increasing in France, especially in deprived districts. The Itineraires Medico-sociaux Programme d'Accompagnement sur un Territoire (IMPACT) intervention is intended for disadvantaged patients with a chronic disease (not only type 2 diabetes). The IMPACT intervention offers coordinated and patient-centered care by a multidisciplinary team with an empowerment approach. This personalised intervention lasts 6 months. This study aims to evaluate the effect of 6 months IMPACT intervention on glycaemic control (glycated haemoglobin - HbA1c) of patients with type 2 diabetes in deprived districts. Method : This will be a randomised, controlled, parallel group, multicenter, open-label trial. 140 adults with type 2 diabetes will be randomised in two arms : IMPACT intervention group (n : 70) and usual care group (n : 70). The primary outcome is change in glycated haemoglobin (HbA1c) from baseline to 6 months. The primary outcome will be analysed using a linear mixed effects model.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
140

participants targeted

Target at P50-P75 for not_applicable diabetes-mellitus-type-2

Timeline
Completed

Started Sep 2021

Typical duration for not_applicable diabetes-mellitus-type-2

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 27, 2020

Completed
8 days until next milestone

First Posted

Study publicly available on registry

November 4, 2020

Completed
10 months until next milestone

Study Start

First participant enrolled

September 1, 2021

Completed
2 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 1, 2023

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2024

Completed
Last Updated

November 4, 2020

Status Verified

November 1, 2020

Enrollment Period

2 years

First QC Date

October 27, 2020

Last Update Submit

November 1, 2020

Conditions

Keywords

primary health carepatient-centered carepoverty areasvulnerable populationsGlycated Hemoglobin A

Outcome Measures

Primary Outcomes (1)

  • HbA1c

    Change in glycated haemoglobin (HbA1c)

    From baseline to 6 months

Secondary Outcomes (9)

  • HbA1c

    From baseline to 3 months

  • Weight

    At Months 3 and 6 from baseline

  • Body mass index

    At Months 3 and 6 from baseline

  • Body fat mass (Bioelectrical impedance analysis)

    At Months 3 and 6 from baseline

  • Body fat percentage (Bioelectrical impedance analysis)

    At Months 3 and 6 from baseline

  • +4 more secondary outcomes

Study Arms (2)

Intervention group

EXPERIMENTAL

IMPACT intervention

Behavioral: IMPACT intervention

Control group

NO INTERVENTION

Usual care

Interventions

A referent is assigned to the patient. A referent is a health worker (nurse, nutritionist, psychologist …). Patient builds with his referent a free care program (without condition or limit). The patient can choose individual consultation (for example : nutrition, tabacology, psychology …) and/or collective care (for example : patient education, physical activity, relaxation …). A community health worker can help patient with his health administrative procedures. This intervention lasts 6 months.

Intervention group

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Patients with type 2 diabetes
  • Live in Hauts de Chambéry, Biollay or Renaudie district
  • Be able to give written consent

You may not qualify if:

  • Severe cognitive or psychological disorder that may affect study understanding
  • Pregnant or breastfeeding women
  • Had IMPACT intervention in the previous 24 months
  • Concurrent participation in another study
  • Concurrent participation in another diabetes educational care program
  • Life expectancy less than 6 months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Related Publications (3)

  • Tricco AC, Ivers NM, Grimshaw JM, Moher D, Turner L, Galipeau J, Halperin I, Vachon B, Ramsay T, Manns B, Tonelli M, Shojania K. Effectiveness of quality improvement strategies on the management of diabetes: a systematic review and meta-analysis. Lancet. 2012 Jun 16;379(9833):2252-61. doi: 10.1016/S0140-6736(12)60480-2. Epub 2012 Jun 9.

    PMID: 22683130BACKGROUND
  • Attridge M, Creamer J, Ramsden M, Cannings-John R, Hawthorne K. Culturally appropriate health education for people in ethnic minority groups with type 2 diabetes mellitus. Cochrane Database Syst Rev. 2014 Sep 4;2014(9):CD006424. doi: 10.1002/14651858.CD006424.pub3.

    PMID: 25188210BACKGROUND
  • Captieux M, Pearce G, Parke HL, Epiphaniou E, Wild S, Taylor SJC, Pinnock H. Supported self-management for people with type 2 diabetes: a meta-review of quantitative systematic reviews. BMJ Open. 2018 Dec 14;8(12):e024262. doi: 10.1136/bmjopen-2018-024262.

    PMID: 30552277BACKGROUND

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Central Study Contacts

Donatien Talon, Resident

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 27, 2020

First Posted

November 4, 2020

Study Start

September 1, 2021

Primary Completion

September 1, 2023

Study Completion

March 1, 2024

Last Updated

November 4, 2020

Record last verified: 2020-11