NCT04615663

Brief Summary

The symptoms caused by mast cell disorders can have a significant impact on the state of health of individuals, constituting a real burden for them, and consequently altering their quality of life. It therefore seems important to clarify the impact on the quality of life, on the psycho-affective sphere, on professional life and on the direct and indirect costs caused by the disease, as well as on the "patient's remaining burden". It seems possible by a longitudinal study (patient follow-up over 1 year). Primary objective is Assessment of quality of life in adult patient with mast cell diseases at M0.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
200

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2020

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 28, 2020

Completed
5 months until next milestone

First Submitted

Initial submission to the registry

June 16, 2020

Completed
5 months until next milestone

First Posted

Study publicly available on registry

November 4, 2020

Completed
3 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 28, 2021

Completed
1.6 years until next milestone

Study Completion

Last participant's last visit for all outcomes

September 15, 2022

Completed
Last Updated

November 4, 2020

Status Verified

November 1, 2020

Enrollment Period

1 year

First QC Date

June 16, 2020

Last Update Submit

November 3, 2020

Conditions

Keywords

Burdenquality of lifemast cell diseasework impairment

Outcome Measures

Primary Outcomes (1)

  • Quality of life of mast cell disorder patients

    Quality of life is evaluated with the WHOQOL-bref questionary. This validated questionnaire in French assesses six dimensions of quality of life.

    Baseline

Secondary Outcomes (2)

  • Mast cell disorder patient's life quality

    6 months

  • Mast cell disorder patient's quality of life

    12 months

Study Arms (2)

face-to-face patients

During this visit, the investigator will complete the SMI score.

Behavioral: Score SMI

Email patients

this visit at M0 + 7d will correspond to the emailing of the Mc\_QoL and Burden\_MCD questionnaires completed by the patient.

Interventions

Score SMIBEHAVIORAL

the investigator will complete the SMI score

face-to-face patients

Eligibility Criteria

Age18 Months - 65 Months
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodProbability Sample
Study Population

Prospective, descriptive study, both transversal and longitudinal, open, monocentric, performed in 200 patients with mast cell disease and follow-up at the CEREMAST Toulouse

You may qualify if:

  • Adult patient (\> 18 years old) with confirmed mast cell disorder according to international criteria
  • Patient affiliated to social security regime

You may not qualify if:

  • Patient under legal protection (guardianship, curators or court order)
  • Patient does not speak French

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Cristina BULAI LIVIDEANU

Toulouse, France

RECRUITING

MeSH Terms

Conditions

MastocytosisMast Cell Activation Disorders

Condition Hierarchy (Ancestors)

Neoplasms, Connective TissueNeoplasms, Connective and Soft TissueNeoplasms by Histologic TypeNeoplasmsImmune System Diseases

Study Officials

  • LIVIDEANU Cristina, MD

    University Hospital, Toulouse

    PRINCIPAL INVESTIGATOR

Central Study Contacts

LIVIDEANU Cristina, MD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

June 16, 2020

First Posted

November 4, 2020

Study Start

January 28, 2020

Primary Completion

January 28, 2021

Study Completion

September 15, 2022

Last Updated

November 4, 2020

Record last verified: 2020-11

Locations