Right Iliac Fossa Treatment-Turkey Audit

NCT04614649 | Completed

• 1 other identifier: RIFT-TR
• Study Type: observational
• Target: 3,358
• Locations: 1 country
• Sites: 1

Brief Summary

Background: Acute appendicitis stands out as a frequently encountered surgical emergency. Despite decades of experience and research, the diagnosis remains a formidable challenge, particularly in young females experiencing acute abdominal pain, where the assessment requires consideration of a broader spectrum of potential causes. An overarching concern lies in the risk of over-treatment, leading to an escalation in unnecessary surgeries, known as the negative appendectomy rate (NAR). This elevated NAR is associated with postoperative complications, prolonged hospital stays, and avoidable healthcare expenditures. Despite international guidelines recommending the routine use of risk prediction models for patients with acute abdominal pain, reported NAR values have reached as high as 28.2% in females and 12.1% in males. Aim: The primary study aim is to identify optimal risk prediction models for acute RIF pain in Turkey. The secondary aims are to audit the normal appendicectomy rate, assess whether these scores have similar efficacy in immigrants, and demonstrate nationwide clinical trends to discuss possible improvements.

Conditions

Abdominal Pain; Appendicitis; Appendicitis Acute

Keywords

appendicitis; appendectomy; right iliac fossa; abdominal pain

Outcome Measures

Primary Outcomes (1)

• Best classification performance among 4 appendicitis scoring systems (for Turkish population)

  Data is used to calculate the four most commonly used adult risk prediction models: Alvarado, the Appendicitis Inflammatory Response (AIR), Raja Isteri Pengiran Anak Saleha Appendicitis (RIPASA), and Adult Appendicitis Score (AAS). Then, the performance of each scoring system will be compared with one another to find the best scoring system among them.

  During admission

Secondary Outcomes (2)

• Normal Appendicectomy Rate (NAR)

  All patients are followed up for 60 days, and data being utilized for NAR calculation is collected within that timeframe.

• Best classification performance among 4 appendicitis scoring systems (for immigrant population)

  During admission

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients referred to general surgeons with right iliac fossa pain or suspected appendicitis.

You may qualify if:

• All consecutive patients referred to general surgeons with right iliac fossa pain or suspected appendicitis.
• All patients who undergo an appendicectomy during the study period.

You may not qualify if:

• Previous appendicectomy, right hemicolectomy, or total colectomy.
• Previous abdominal surgery in the last 90 days.
• Pregnancy.
• Patients confirmed with COVID-19.

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Gazi University

Ankara, 06560, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Abdominal Pain; Appendicitis

Condition Hierarchy (Ancestors)

Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Signs and Symptoms, Digestive; Intraabdominal Infections; Infections; Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Cecal Diseases; Intestinal Diseases

Study Officials

• Sezai Leventoglu, Professor

  Gazi University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 60 Days
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Dr.

Study Record Dates

• First Submitted: October 29, 2020
• First Posted: November 4, 2020
• Study Start: September 10, 2020
• Primary Completion: December 31, 2020
• Study Completion: March 1, 2021
• Last Updated: February 8, 2024

Record last verified: 2024-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)