Inter-rater Reliability of the Australian Spasticity Assessment Scale (ASAS) in Post-stroke Spasticity

NCT04613661 | Completed

• 1 other identifier: 2020-GOKAE-0450
• Study Type: observational
• Target: 85
• Locations: 1 country
• Sites: 1

Brief Summary

The reliability of the Australian Spasticity Assessment Scale (ASAS) has been reported to be not high enough in adult patients with acquired brain damage. The low number of patients and the heterogeneous study population have been reported as important limitations in the reliability study of this measure. Therefore, the reliability of the ASAS needs to be confirmed in stroke patients with spasticity. This study aims to investigate the inter-rater reliability of the ASAS in a study population consisting of a larger and more homogeneous patient population (those with post-stroke spasticity).

Conditions

Hemiplegia, Spastic

Keywords

Hemiplegia; spasticity; upper limb

Outcome Measures

Primary Outcomes (1)

• Australian Spasticity Assessment Scale (ASAS)

  The ASAS is an ordinal scale with five levels (0, 1, 2, 3, 4). The severity of spasticity increases as the level-ups.The contracture is assessed separately. Level 0 means no catch on rapid passive stretch (no spasticity), and level 4 means that the body part is fixed on the rapid passive stretch but moves on the slow passive stretch. In level 1, a catch followed by a release occurs on the rapid passive stretch. In level 2, the catch is in the second half of the range, and there is a resistance in the remaining range of motion. In level 3, the catch is in the first half of the range, and there is a resistance in the remaining range of motion.

  Through study completion, an average of 2 year

Study Arms (2)

Researcher 1

The first researcher assessing elbow, wrist, and ankle spasticity, respectively

Other: Australian Spasticity Assessment Scale

Researcher 2

The second researcher assessing elbow, wrist, and ankle spasticity, respectively

Other: Australian Spasticity Assessment Scale

Interventions

Australian Spasticity Assessment Scale OTHER

Australian Spasticity Assessment Scale is a clinical measure to assess the severity of spasticity

Researcher 1; Researcher 2

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Chronic stroke patients with elbow and/or wrist and /or ankle spasticity

You may qualify if:

• Chronic stroke (\> 6 months)
• Fist stroke
• Increased tone according to the Modified Ashworth Scale in at least one of the elbow, wrist, and ankle
• Stability of spasticity for the last 3 months

You may not qualify if:

• Increased tone due to causes other than stroke (traumatic brain injury, spinal cord injury, multiple sclerosis, motor neuron disease, etc.)
• Acute or subacute stroke (≤6 months)
• Recurrent stroke attacks
• Presence of contracture and/or moderate to severe pain in the joints to be assessed (elbow, wrist, and ankle)
• Botulinum toxin injection in the last three months
• History of neurolysis for spasticity (alcohol or phenol)
• History of surgery for spasticity
• Initiation of a new drug for spasticity, or a change in drug dose

Sponsors & Collaborators

• Izmir Katip Celebi University: lead

Study Sites (1)

İlker Şengül

Izmir, 35360, Turkey (Türkiye)

Location

Related Publications (7)

• Lance JW. The control of muscle tone, reflexes, and movement: Robert Wartenberg Lecture. Neurology. 1980 Dec;30(12):1303-13. doi: 10.1212/wnl.30.12.1303. No abstract available.

  PMID: 7192811 BACKGROUND

• Lundstrom E, Terent A, Borg J. Prevalence of disabling spasticity 1 year after first-ever stroke. Eur J Neurol. 2008 Jun;15(6):533-9. doi: 10.1111/j.1468-1331.2008.02114.x. Epub 2008 Mar 18.

  PMID: 18355307 BACKGROUND

• Wissel J, Manack A, Brainin M. Toward an epidemiology of poststroke spasticity. Neurology. 2013 Jan 15;80(3 Suppl 2):S13-9. doi: 10.1212/WNL.0b013e3182762448.

  PMID: 23319481 BACKGROUND

• Pierson SH. Outcome measures in spasticity management. Muscle Nerve Suppl. 1997;6:S36-60.

  PMID: 9826982 BACKGROUND

• Bohannon RW, Smith MB. Interrater reliability of a modified Ashworth scale of muscle spasticity. Phys Ther. 1987 Feb;67(2):206-7. doi: 10.1093/ptj/67.2.206.

  PMID: 3809245 BACKGROUND

• Love S, Gibson N, Smith N, Bear N, Blair E; Australian Cerebral Palsy Register Group. Interobserver reliability of the Australian Spasticity Assessment Scale (ASAS). Dev Med Child Neurol. 2016 Feb;58 Suppl 2:18-24. doi: 10.1111/dmcn.13000. Epub 2016 Jan 14.

  PMID: 26762706 BACKGROUND

• Calame A, Singer B. Inter- and Intra-Rater Reliability of the Australian Spasticity Assessment Scale in Adults with Acquired Brain Injury. Open Journal of Therapy and Rehabilitation. 2015;3:77-86.

  BACKGROUND

MeSH Terms

Conditions

Hemiplegia; Muscle Spasticity

Condition Hierarchy (Ancestors)

Paralysis; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Muscular Diseases; Musculoskeletal Diseases; Muscle Hypertonia; Neuromuscular Manifestations

Study Officials

• İlker Şengül, M.D.

  İzmir Katip Çelebi University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal Investigator

Study Record Dates

• First Submitted: October 23, 2020
• First Posted: November 3, 2020
• Study Start: October 20, 2020
• Primary Completion: December 17, 2021
• Study Completion: December 17, 2021
• Last Updated: February 15, 2022

Record last verified: 2022-02

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)