Determination of Risk Factors for the Development of Obesity and Hypertension in Children According to Perinatal Programming of Metabolism

NCT04611412 | Unknown

• 1 other identifier: Project #4
• Study Type: observational
• Target: 55
• Locations: 1 country
• Sites: 1

Brief Summary

to determine the risk factors for developing obesity in children with exogenous-constitutional obesity and arterial hypertension, according to the theories of early programming of metabolism

Conditions

Metabolic Syndrome

Keywords

Metabolic Syndrome; children; obesity

Outcome Measures

Primary Outcomes (1)

• Risk factors of metabolic syndrome

  A retrospective, cohort study of 55 children aged 12 to 18 years with exogenous constitutional obesity will be conducted Children with exogenous-constitutional obesity were divided by the presence of abdominal (visceral) obesity and the presence of hypertension. Parents will be interviewed and medical records (forms 003/y and 112) of children with exogenous constitutional obesity will be analyzed. Also, on the basis of a specially developed questionnaire, children with exogenous constitutional obesity were surveyed. When conducting a survey of children and their parents, the following factors will be of particular importance: heredity, pregnancy, weight and body length at birth, the nature of nutrition in the first two years of life, eating habits, and physical activity.

  up to 36 months

Study Arms (2)

1 group

Group I consisted of 17 people (16.83%) with a uniform type of obesity

Other: Risk Factors

2 group

Group II included 38 children with AO, and 20 of them had normal BLOOD pressure

Other: Risk Factors

Interventions

Risk Factors OTHER

BMI in children and adolescents was compared with percentile charts developed by who for children from 5 to 19 years of age (WHO Growth Reference, 2007). Body mass index was defined as the ratio of body weight (in kg) to body length in the supine position or height in the standing position (m2).

1 group; 2 group

Eligibility Criteria

• Age: 12 Years - 18 Years
• Sex: all
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Probability Sample

Study Population

the cohort study will include 55 children aged 12 to 18 with exogenous constitutional obesity

You may qualify if:

• SDS (standart deviation score) of body mass index (BMI) ranging from +2.0 to +3.0

You may not qualify if:

• secondary obesity and overweight genetic syndromes,
• refusal of the child and/or parents to be examined

Sponsors & Collaborators

• Samarkand State Medical Institute: lead

Study Sites (1)

Samarkand State Medical Institute

Samarkand, 140100, Uzbekistan

RECRUITING

MeSH Terms

Conditions

Metabolic Syndrome; Obesity

Interventions

Risk Factors

Condition Hierarchy (Ancestors)

Insulin Resistance; Hyperinsulinism; Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Overweight; Overnutrition; Nutrition Disorders; Body Weight; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Risk; Probability; Statistics as Topic; Epidemiologic Methods; Investigative Techniques; Causality; Epidemiologic Factors; Quality of Health Care; Health Care Quality, Access, and Evaluation; Health Care Evaluation Mechanisms; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 11, 2020
• First Posted: November 2, 2020
• Study Start: December 15, 2020
• Primary Completion: December 30, 2023
• Study Completion: January 2, 2024
• Last Updated: November 2, 2020

Record last verified: 2020-10

Data Sharing

• IPD Sharing: Will not share

Locations

UZ (1)