Dose Surgical Pleth Index Play a Role to Predict Optimal Timing for Tracheal Intubation During Anesthetic Induction?
Sponsor study identifier
observational
102
1 country
1
Study Start
September 30, 2020
Actual (reported)Primary Completion
November 28, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
November 30, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Surgical pleth index (SPI) has been widely investigated in assessing the nociceptive level, and tracheal intubation is a noxious stimulus during the induction of anesthesia. This study aims to evaluate the ability of SPI to predict hemodynamic reactivity after tracheal intubation, and find the target value of SPI to guide the optimal timing for tracheal intubation.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
November 30, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
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Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
September 30, 2020
Actual (reported)October 2, 2020
Actual (reported)October 29, 2020
Actual (reported)November 28, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
November 30, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
ability of SPI to predict hemodynamic reactivity after tracheal intubation in general population
The area under receiver-operating characteristic curve (AUC) of SPI
within 2 minutes after trachea intubation
ability of SPI to predict hemodynamic reactivity after tracheal intubation in female
The area under receiver-operating characteristic curve (AUC) of SPI
within 2 minutes after trachea intubation
ability of SPI to predict hemodynamic reactivity after tracheal intubation in male
The area under receiver-operating characteristic curve (AUC) of SPI
within 2 minutes after trachea intubation
influence factors of hemodynamic reactivity
within 2 minutes after trachea intubation
Cardiovascular stress level
within 2 minutes after trachea intubation
American Society of Anesthesiology physical status (ASA) 1-2 and patients aged 18-80 years undergoing non-emergency anesthesia
Department of Anesthesiology, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University
Shanghai, Shanghai Municipality, 200032, China
Huiku M, Uutela K, van Gils M, Korhonen I, Kymalainen M, Merilainen P, Paloheimo M, Rantanen M, Takala P, Viertio-Oja H, Yli-Hankala A. Assessment of surgical stress during general anaesthesia. Br J Anaesth. 2007 Apr;98(4):447-55. doi: 10.1093/bja/aem004. Epub 2007 Feb 28.
Struys MM, Vanpeteghem C, Huiku M, Uutela K, Blyaert NB, Mortier EP. Changes in a surgical stress index in response to standardized pain stimuli during propofol-remifentanil infusion. Br J Anaesth. 2007 Sep;99(3):359-67. doi: 10.1093/bja/aem173. Epub 2007 Jul 3.
Jun Zhang, PhD
Fudan University
First Submitted
October 2, 2020
First Posted
October 29, 2020
Study Start
September 30, 2020
Actual (reported)Primary Completion
November 28, 2021
Estimated (date passed)Contact the study team to confirm eligibility.
Bergmann I, Gohner A, Crozier TA, Hesjedal B, Wiese CH, Popov AF, Bauer M, Hinz JM. Surgical pleth index-guided remifentanil administration reduces remifentanil and propofol consumption and shortens recovery times in outpatient anaesthesia. Br J Anaesth. 2013 Apr;110(4):622-8. doi: 10.1093/bja/aes426. Epub 2012 Dec 5.
This estimate has passed. The registry has not confirmed an actual date for this milestone.
Study Completion
November 30, 2021
Estimated (date passed)This estimate has passed. The registry has not confirmed an actual date for this milestone.
Last Updated
December 2, 2021
Record last verified: 2021-11
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