Evaluation of Quality of Life and Its Influencing Factors After VA-ECMO in Refractory Cardiac Arrest Based on SF-36 Score : A Grenoble Cohort Study From 2006 Through 2018

NCT04601896 | Completed

• 2 other identifiers: 38RC20.2252020-A01859-30
• Study Type: observational
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

If the ExtraCorporeal Membrane Oxygenation (ECMO) improves survival in the management of refractory cardiac arrest (RCA), this technique is still an invasive technique, not devoid of complications and requiring intensive care that can have serious consequences for patients. If the studies so far show an acceptable quality of life post ECMO in refractory cardiac arrest, the study looks about the quality of life of our patients in Grenoble who survived a refractory cardiac arrest between 2006 and 2018 at the hospital university Grenoble Alps and the factors influencing this quality of life.

Conditions

Refractory Cardiac Arrest; ExtraCorporeal Membrane Oxygenation (ECMO)

Keywords

ExtraCorporeal Membrane Oxygenation (ECMO); Refractory Cardiac Arrest; Quality life assessement (SF36 QUESTIONNAIRE)

Outcome Measures

Primary Outcomes (1)

• Global quality of life score

  Items from the SF36 (Short Form 36) survey

  Through study completion, an average of 3 months

Secondary Outcomes (4)

• Live patients characteristics description

  Through study completion, an average of 3 months

• Vital status

  Through study completion, an average of 3 months

• Quality of life score related at live patients characteristics description

  Through study completion, an average of 3 months

• Quality of life score comparison

  Through study completion, an average of 3 months

Study Arms (2)

Live patients admitted for Refractory Cardiac Arrest with ECMO

Other: SF36 questionnaire via telephone interview

Live patients quality of life admitted for Refractory Cardiac Arrest without ECMO

Other: SF36 questionnaire via telephone interview

Interventions

SF36 questionnaire via telephone interview OTHER

SF36 questionnaire via telephone interview

Live patients admitted for Refractory Cardiac Arrest with ECMO; Live patients quality of life admitted for Refractory Cardiac Arrest without ECMO

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

monocentric study based on clinical data and quality of life assessement, Retrospective step : * Clinical data collection for live patients admissed for Refractory Cardiac Arrest with ECMO from january 2006 through december 2018, * Clinical data collection for live patients admissed for Refractory Cardiac Arrest without ECMO from january 2015 through december 2018, Prospective step: * Quality of life assessment via telephone interview based on SF36 questionnaire performed for live patients admissed for Refractory Cardiac Arrest with ECMO from january 2006 through december 2018 * Quality of life assessment via telephone interview based on SF36 questionnaire performed for live patients admissed for Refractory Cardiac Arrest without ECMO from january 2015 through december 2018

You may qualify if:

• Adult \>18 years
• Admission to intensive care unit after a Refractory Cardiac Arrest
• Hemodynamic instability after resumption of spontaneous cardiac activity.
• Non-opposition of the patient or his relatives
• Admission to intensive care unit From 2006 Through 2018

You may not qualify if:

• ECMO for hypothermia or drug intoxication.
• Comorbidity contraindicated the ECMO
• Patients dead before hospital discharge

Sponsors & Collaborators

• University Hospital, Grenoble: lead

Study Sites (1)

Chu Grenoble Alpes

Grenoble, 38043, France

Location

MeSH Terms

Conditions

Heart Arrest

Condition Hierarchy (Ancestors)

Heart Diseases; Cardiovascular Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Target Duration: 1 Day
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: October 13, 2020
• First Posted: October 26, 2020
• Study Start: October 16, 2020
• Primary Completion: January 15, 2021
• Study Completion: April 27, 2021
• Last Updated: April 30, 2021

Record last verified: 2020-12

Locations

FR (1)