NCT04600882

Brief Summary

This single-center, observational study is being conducted to identify a well-characterized subgroup within the ASD patient population, based on clinical symptoms and biosample analysis.

Trial Health

30
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Timeline
Completed

Started Nov 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
withdrawn

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 19, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

October 23, 2020

Completed
1 month until next milestone

Study Start

First participant enrolled

November 30, 2020

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 31, 2021

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

April 30, 2021

Completed
Last Updated

August 31, 2022

Status Verified

August 1, 2022

Enrollment Period

4 months

First QC Date

October 19, 2020

Last Update Submit

August 30, 2022

Conditions

Keywords

autism spectrum disorderendophenotypingobservational

Outcome Measures

Primary Outcomes (1)

  • Prevalence of non-behavioral phenotypical traits in sub-populations with Autism Spectrum Disorder (ASD)

    A questionnaire will be administered to collect non-behavioral traits and co-occurring conditions data of the participants

    Day 0

Eligibility Criteria

Age4 Years - 10 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17)
Sampling MethodNon-Probability Sample
Study Population

Nationwide Children's Hospital Primary Care Clinic

You may qualify if:

  • Previously diagnosed with ASD (based on DSM-5 criteria and supported by either ADI-R or ADOS-2 scores)
  • At least two well documented head circumference values recorded within the first 2 years of life
  • Participants must have a parent or reliable caregiver who agrees to provide information about the participant as required by the protocol and should be fluent in English

You may not qualify if:

  • Genetically identified ASD (syndromic form of autism, e.g. fragile X)
  • Episode of fever (i.e. ≥100.5 °F) or clinically significant illness without fever (as judged by the Investigator), within 10 days before the study visit

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Nationwide Children's Hospital

Columbus, Ohio, 43205, United States

Location

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, PervasiveNeurodevelopmental DisordersMental Disorders
0

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

October 19, 2020

First Posted

October 23, 2020

Study Start

November 30, 2020

Primary Completion

March 31, 2021

Study Completion

April 30, 2021

Last Updated

August 31, 2022

Record last verified: 2022-08

Locations