NCT04592107

Brief Summary

The visceral adiposity index (VAI) has been developed, an indicator for the metabolic function of VAT. Previous studies have confirmed the association between the VAI and CKD prevalence. In this study, we attempted to investigate the association between estimated glomerular filtration rate (eGFR) decline and visceral adiposity.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
129

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2017

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 12, 2017

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 30, 2018

Completed
7 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2019

Completed
1.3 years until next milestone

First Submitted

Initial submission to the registry

October 12, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 19, 2020

Completed
Last Updated

October 19, 2020

Status Verified

October 1, 2020

Enrollment Period

12 months

First QC Date

October 12, 2020

Last Update Submit

October 12, 2020

Conditions

Keywords

obesitychronic kidney diseasediabetes mellitus

Outcome Measures

Primary Outcomes (1)

  • progression of chronic kidney disease

    increase in eGFR of chronic kidney disease patients in one year

    one year

Interventions

eGFRDIAGNOSTIC_TEST

estimated glomerular filtration rate

Eligibility Criteria

Age10 Years - 80 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Chronic kidney disease patients who were followed up in the Nephrology Department of the Usak University Research and Training Hospital for at least 1 year between December 2017 and November 2018.

You may qualify if:

  • patients with stage 2-5 CKD
  • aged 18 and 80 years
  • were not on dialysis
  • patients were followed up in the Nephrology Department of the Usak University Research and Training Hospital for at least 1 year between December 2017 and November 2018.

You may not qualify if:

  • missing data, patients older than 80 years, patients taking cholesterol and lipid lowering drugs and/or steroids.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Usak University

Uşak, Select One, 64200, Turkey (Türkiye)

Location

Related Publications (2)

  • Kramer H, Luke A, Bidani A, Cao G, Cooper R, McGee D. Obesity and prevalent and incident CKD: the Hypertension Detection and Follow-Up Program. Am J Kidney Dis. 2005 Oct;46(4):587-94. doi: 10.1053/j.ajkd.2005.06.007.

    PMID: 16183412BACKGROUND
  • Amato MC, Giordano C. Visceral adiposity index: an indicator of adipose tissue dysfunction. Int J Endocrinol. 2014;2014:730827. doi: 10.1155/2014/730827. Epub 2014 Apr 14.

    PMID: 24829577BACKGROUND

MeSH Terms

Conditions

Obesity, AbdominalRenal Insufficiency, ChronicDiabetes MellitusObesity

Condition Hierarchy (Ancestors)

OverweightOvernutritionNutrition DisordersNutritional and Metabolic DiseasesBody WeightSigns and SymptomsPathological Conditions, Signs and SymptomsRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesGlucose Metabolism DisordersMetabolic DiseasesEndocrine System Diseases

Study Officials

  • Zelal Adibelli

    Uşak University

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Target Duration
1 Year
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Prof. Zelal Adibelli

Study Record Dates

First Submitted

October 12, 2020

First Posted

October 19, 2020

Study Start

December 12, 2017

Primary Completion

November 30, 2018

Study Completion

June 30, 2019

Last Updated

October 19, 2020

Record last verified: 2020-10

Locations