NCT04584931

Brief Summary

Treatment of gingival recession requires favourable anatomical conditions and the use of invasive surgical approaches. Hence, these procedures are not always indicated in all cases and can cause great pain and morbidity. Coloured composite restorations that mimic the lost gingival tissues can provide a non-invasive and simple solution regardless of the recession soft and hard-tissue conditions.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
20

participants targeted

Target at below P25 for not_applicable

Timeline
Completed

Started Oct 2021

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

October 3, 2020

Completed
11 days until next milestone

First Posted

Study publicly available on registry

October 14, 2020

Completed
12 months until next milestone

Study Start

First participant enrolled

October 1, 2021

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 30, 2022

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 30, 2022

Completed
Last Updated

October 14, 2020

Status Verified

October 1, 2020

Enrollment Period

12 months

First QC Date

October 3, 2020

Last Update Submit

October 10, 2020

Conditions

Outcome Measures

Primary Outcomes (1)

  • post-operative pain

    self-reported pain on visual analogue scale (VAS)

    7 days

Secondary Outcomes (9)

  • post-operative pain

    1,3,5,14 days

  • overall quality of life: questionnaire

    6 months

  • Reported post-operative satisfaction

    6 months

  • mean root coverage

    6 months

  • complete root coverage

    6 months

  • +4 more secondary outcomes

Study Arms (2)

Treatment of gingival recession with colored composite

EXPERIMENTAL

Composite restoration will be applied to the gingival recession defect

Procedure: restorative intervention

Treatment of gingival recession with coronally advanced flap

ACTIVE COMPARATOR

coronally advanced flap at the gingival defect

Procedure: coronally advanced flap

Interventions

flap surgery to achieve root coverage at gingival recession defect

Treatment of gingival recession with coronally advanced flap

colored composite restoration to camouflage the gingival recession defect

Treatment of gingival recession with colored composite

Eligibility Criteria

Age18 Years - 60 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • participants with at least one buccal gingival recession
  • O'Leary plaque index less than 20%
  • motivated participants willing to complete the follow up

You may not qualify if:

  • prior surgical or restorative interventions at the recession defect
  • smokers
  • pregnant participants
  • systemic conditions contraindicating dental management

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Gingival Recession

Condition Hierarchy (Ancestors)

Gingival DiseasesPeriodontal DiseasesMouth DiseasesStomatognathic DiseasesPeriodontal Atrophy

Central Study Contacts

Karim Fawzy El-Sayed, PhD

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NON RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Lecturer

Study Record Dates

First Submitted

October 3, 2020

First Posted

October 14, 2020

Study Start

October 1, 2021

Primary Completion

September 30, 2022

Study Completion

December 30, 2022

Last Updated

October 14, 2020

Record last verified: 2020-10

Data Sharing

IPD Sharing
Will not share