NCT04584138

Brief Summary

This study aims at the assessment of eye movement during autobiographical retrieval (i.e., retrieval of personal memories) in patients with Alzheimer's Disease.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
54

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Apr 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 23, 2020

Completed
19 days until next milestone

First Posted

Study publicly available on registry

October 12, 2020

Completed
6 months until next milestone

Study Start

First participant enrolled

April 15, 2021

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

November 25, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

November 25, 2022

Completed
Last Updated

March 23, 2023

Status Verified

March 1, 2023

Enrollment Period

1.6 years

First QC Date

September 23, 2020

Last Update Submit

March 22, 2023

Conditions

Alzheimer's DiseaseAutobiographical MemoryEye MovementMemory

Outcome Measures

Primary Outcomes (2)

  • Number of fixations and saccades

    Number

    Four weeks (from assessment till analysis)

  • Duration of fixations and saccades

    Duration in milliseconds

    Four weeks (from assessment till analysis)

Secondary Outcomes (1)

  • Pupil size

    Four weeks (from assessment till analysis)

Interventions

Study of eye movementsBEHAVIORAL

The assessment of eye movement during autobiographical retrieval (i.e., retrieval of personal memories) in patients with Alzheimer's Disease.

Eligibility Criteria

Age18 Years - 100 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients diagnosed with Alzheimer's disease in the mild stage

You may qualify if:

  • Diagnosis of Alzheimer's Disease at the mild stage

You may not qualify if:

  • Neurological/psychiatric disorders (other than Alzheimer's Disease)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

CHU de Nantes

Nantes, 44000, France

Location

Related Publications (1)

  • El Haj M, M J Janssen S, Gallouj K, Lenoble Q. Autobiographical Memory Increases Pupil Dilation. Transl Neurosci. 2019 Dec 19;10:280-287. doi: 10.1515/tnsci-2019-0044. eCollection 2019.

    PMID: 31915538RESULT

Related Links

MeSH Terms

Conditions

Alzheimer Disease

Condition Hierarchy (Ancestors)

DementiaBrain DiseasesCentral Nervous System DiseasesNervous System DiseasesTauopathiesNeurodegenerative DiseasesNeurocognitive DisordersMental Disorders

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 23, 2020

First Posted

October 12, 2020

Study Start

April 15, 2021

Primary Completion

November 25, 2022

Study Completion

November 25, 2022

Last Updated

March 23, 2023

Record last verified: 2023-03

Data Sharing

IPD Sharing
Will not share

Locations

FR(1)