NCT04578340

Brief Summary

The objective of this study is to establish the extent to which mesh improves quality of life and surgical outcomes following hernia repair.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
4,700

participants targeted

Target at P75+ for all trials

Timeline
5mo left

Started Oct 2020

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress93%
Oct 2020Oct 2026

First Submitted

Initial submission to the registry

October 1, 2020

Completed
Same day until next milestone

Study Start

First participant enrolled

October 1, 2020

Completed
7 days until next milestone

First Posted

Study publicly available on registry

October 8, 2020

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 1, 2025

Completed
1 year until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2026

Expected
Last Updated

November 14, 2023

Status Verified

November 1, 2023

Enrollment Period

5 years

First QC Date

October 1, 2020

Last Update Submit

November 11, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • Hernia recurrence rate

    Should the hernia repair fail and the hernia reappears, this is counted as a recurrent hernia.

    Within 5 years of initial hernia repair

  • Patient quality of life

    Quality of life before and after surgery will be compared using various self-reported assessment tools/questionnaires.

    Up to 5 years postopertively

Secondary Outcomes (1)

  • Postoperative infection rate

    Up to 5 years postoperatively

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Multihospital system inclusive of all abdominal hernia repairs using mesh

You may qualify if:

  • abdominal hernia repair using mesh

You may not qualify if:

  • less than 18 years old

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NorthShore University HealthSystem

Evanston, Illinois, 60201, United States

RECRUITING

MeSH Terms

Conditions

Hernia, Abdominal

Condition Hierarchy (Ancestors)

HerniaPathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
5 Years
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director of Minimally Invasive Surgery; Chief, Division of Gastrointestinal and General Surgery

Study Record Dates

First Submitted

October 1, 2020

First Posted

October 8, 2020

Study Start

October 1, 2020

Primary Completion

October 1, 2025

Study Completion (Estimated)

October 1, 2026

Last Updated

November 14, 2023

Record last verified: 2023-11

Data Sharing

IPD Sharing
Will not share

Locations