NCT04576884|Completed
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Sponsor study identifier
observational
129
1 country
1
Study Start
April 1, 2019
Actual (reported)Primary Completion
May 31, 2019
Actual (reported)Study Completion
January 30, 2020
Actual (reported)The ocular biometric parameters of the human crystalline lens including anterior chamber depth (ACD), lens thickness (LT), radii of curvature of anterior and posterior lens (ALR and PLR), lens equatorial diameter (LED), and lens vault (LV), automatically quantified by the CASIA2 (SS-OCT; Tomey, Nagoya, Japan). Images of iridocorneal angle were obtained using CASIA2 and the Schlemm' s canal (SC) and trabecular meshwork (TM) were quantified manually. Both cycloplegia and non-cycloplegia images were obtained.
Registry-reported information. Elapsed time and enrollment totals alone do not measure study progress or recruitment pace.
January 30, 2020
Actual (reported)Click on a node to explore related trials.
Dates and qualifiers reported by the registry. Estimated dates do not confirm that a milestone has occurred.
April 1, 2019
Actual (reported)May 31, 2019
Actual (reported)January 30, 2020
Actual (reported)September 21, 2020
Actual (reported)October 6, 2020
Actual (reported)Paired Comparison Before and After Cycloplegia
The cycloplegia-induced differences of parameters was defined as: the post-cycloplegic value minus the pre-cycloplegic value.
2020.2.3
Evaluated the effect of age on the TM/SC morphologies
The age-related variations of TM/SC parameters from four age groups were compared.
2020.2.3
Evaluated the effect of age on the ocular biometric data
2020.2.3
participants of less than 18 years old
participants aged from 18 years to 40 year
participants aged from 41 years to 60 years
participants over 60 years old
Healthy individuals aged between 6 and 90 years, without history of ocular disease (except age-related cataract and/or myopia) at Eye hospital of Wenzhou Medical University
Ophthalmology and Optometry Hospital
Wenzhou, Zhejiang, 325027, China
Li Z, Meng Z, Qu W, Li X, Chang P, Wang D, Zhao Y. The Relationship Between Age and the Morphology of the Crystalline Lens, Ciliary Muscle, Trabecular Meshwork, and Schlemm's Canal: An in vivo Swept-Source Optical Coherence Tomography Study. Front Physiol. 2021 Nov 19;12:763736. doi: 10.3389/fphys.2021.763736. eCollection 2021.
Yune Zhao
Ophthalmology and Optometry Hospital
129 participants (actual enrollment reported by the registry).
First Submitted
September 21, 2020
First Posted
October 6, 2020
Study Start
April 1, 2019
Actual (reported)Evaluation of the Rotational Stability of The AcrySof Toric Intraocular Lens in the Capsular Bag in High Myopic Subjects
Contact the study team to confirm eligibility.
Primary Completion
May 31, 2019
Actual (reported)Study Completion
January 30, 2020
Actual (reported)Last Updated
October 6, 2020
Record last verified: 2020-09
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Source: ClinicalTrials.gov.
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