NCT04569422

Brief Summary

In this study, there were differences in patients' demands for ephedrine during meibomian gland massage and whether it would affect patients' poor comfort. Therefore, we needed to collect patients' pain grades during meibomian gland massage

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jun 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

June 1, 2020

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

September 24, 2020

Completed
5 days until next milestone

First Posted

Study publicly available on registry

September 29, 2020

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

March 21, 2021

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 21, 2021

Completed
Last Updated

September 29, 2020

Status Verified

September 1, 2020

Enrollment Period

10 months

First QC Date

September 24, 2020

Last Update Submit

September 24, 2020

Conditions

Meibomian Gland Massage is Important to Delay the Development of Meibomian Gland Dysfunction

Outcome Measures

Primary Outcomes (1)

  • Undifferrentiated

    There was no difference in the effect of obuvacaine hydrochloride on the comfort of meibomian gland massage patients

    2020.01-2020.09

Study Arms (1)

ephedrine drop

Drug: Benoxyl

Interventions

BenoxylDRUG

reduce pain

ephedrine drop

Eligibility Criteria

Age18 Years - 80 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodProbability Sample
Study Population

Meibomian gland dysfunction people with no chronic disease

You may qualify if:

  • Healthy people with no chronic disease

You may not qualify if:

  • People with chronic disease

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Aier School of Ophthalmology, Central South University

Changsha, Hunan, China

RECRUITING

MeSH Terms

Interventions

Benzoyl Peroxide

Intervention Hierarchy (Ancestors)

BenzoatesAcids, CarbocyclicCarboxylic AcidsOrganic ChemicalsBenzene DerivativesHydrocarbons, AromaticHydrocarbons, CyclicHydrocarbons

Study Officials

  • Yuanyuan Yin, bachelor

    Shanghai Aier Eye Hospital

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Yuanyuan Yin, bachelor

CONTACT

18621755180815969138@qq.com

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Influence of Obuvacaine Hydrochloride Eye Drops on the Comfort of Meibomian Gland Massage Patients

Study Record Dates

First Submitted

September 24, 2020

First Posted

September 29, 2020

Study Start

June 1, 2020

Primary Completion

March 21, 2021

Study Completion

May 21, 2021

Last Updated

September 29, 2020

Record last verified: 2020-09

Locations

CN(1)