Palmoplantar Pustulosis and Generalized Pustular Psoriasis: A National Population-based Analysis of Prevalence

NCT04566471 | Unknown

• 1 other identifier: BI13680065
• Study Type: observational
• Target: 200
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study plans to calculate the prevalence and incidence of palmoplantar pustulosis and generalized pustular psoriasis based on the national medical insurance data and analyze the composition characteristics and some clinical features of patients, through taking into account of the research status of palmoplantar pustulosis and generalized pustular psoriasis and the characteristics of medical insurance data.

Conditions

Palmoplantar Pustulosis; Generalized Pustular Psoriasis

Keywords

Generalized pustular psoriasis; Palmoplantar pustulosis; Urban Employee Basic Medical Insurance (UEBMI) data; prevalence; incidence

Outcome Measures

Primary Outcomes (2)

• prevalence of Palmoplantar pustulosis

  Epidemiological characteristics of diseases: Mainly referring to indicators that could reflect the frequency related to the disease

  From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China

• prevalence of Generalized pustular psoriasis

  Epidemiological characteristics of diseases: Mainly referring to indicators that could reflect the frequency related to the disease

  From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China

Secondary Outcomes (4)

• incidence of Palmoplantar pustulosis

  From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China

• incidence of Generalized pustular psoriasis

  From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China

• Economic burden of Palmoplantar pustulosis

  From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China

• Economic burden of Generalized pustular psoriasis

  From 2012 to 2016 in the Urban Employee Basic Medical Insurance (UEBMI) data of China

Study Arms (1)

PPP and GPP

Palmoplantar pustulosis (PPP) and Generalized pustular psoriasis (GPP) are rare chronic inflammatory skin diseases, characterized by repeated episodes of sterile pustules in several months or years, associated with erythrokeratodermia generally. Both two diseases are easy to cause skin rupture, leading to bleeding and pain.

Other: prevalence/incidence

Interventions

prevalence/incidence OTHER

It is an observational study for prevalence/incidence, no intervention provided.

PPP and GPP

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

This study used the Urban Employee Basic Medical Insurance (UEBMI) data from 2012 to 2016 to calculate the epidemiological characteristics of palmoplantar pustulosis and generalized pustular psoriasis. The database includes basic medical insurance data for urban workers and basic medical insurance data for urban residents, which covers 31 provinces, municipalities and autonomous regions. By the end of 2016, the number of people participating in the national basic medical insurance exceeded 1.3 billion, and the coverage rate of the insurance was stable at over 95%. The database is composed of an insurance coverage database and a reimbursement settlement database. The insurance coverage database involves demographic information, insurance information and payment information; and the reimbursement settlement database involves medical information, disease information and expense information.

You may qualify if:

• The insured population of the national urban employee basic medical insurance and the urban resident basic medical insurance from January 1, 2012, to December 31, 2016 (60 months) (the denominator)
• The patients have been diagnosed with palmoplantar pustulosis or generalized pustular psoriasis (including disease name, English abbreviation and ICD code)
• Both outpatient and inpatient patients are included

You may not qualify if:

• The individuals whose information is only contained in the reimbursement settlement database but not in the insurance coverage database will be considered as invalid reimbursement individuals and be excluded from the study (the denominator)
• The patients have been diagnosed with non-PPP and -GPP diseases, such as pustular psoriasis in palm and toe, pustular arthritis osteitis and SAPHO syndrome

Sponsors & Collaborators

• Peking University Third Hospital: lead

MeSH Terms

Conditions

Psoriasis

Interventions

Prevalence; Incidence

Condition Hierarchy (Ancestors)

Skin Diseases, Papulosquamous; Skin Diseases; Skin and Connective Tissue Diseases

Intervention Hierarchy (Ancestors)

Morbidity; Vital Statistics; Data Collection; Epidemiologic Methods; Investigative Techniques; Demography; Population Characteristics; Epidemiologic Measurements; Public Health; Environment and Public Health

Study Officials

• Siyan Zhan, PhD

  Peking University Third Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 22, 2020
• First Posted: September 28, 2020
• Study Start: January 1, 2012
• Primary Completion: December 1, 2016
• Study Completion: December 31, 2021
• Last Updated: September 28, 2020

Record last verified: 2020-06

Data Sharing

• IPD Sharing: Will not share