NCT04563247

Brief Summary

This study is about the current knowledge on the immunological changes observed in various healthcare workers in this part of the world, who remained asymptomatic while working in high exposure areas of COVID-19 infection.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
970

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jul 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

July 1, 2020

Completed
3 months until next milestone

First Submitted

Initial submission to the registry

September 20, 2020

Completed
4 days until next milestone

First Posted

Study publicly available on registry

September 24, 2020

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 8, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

February 8, 2021

Completed
Last Updated

February 15, 2022

Status Verified

February 1, 2022

Enrollment Period

7 months

First QC Date

September 20, 2020

Last Update Submit

February 12, 2022

Conditions

Covid19

Outcome Measures

Primary Outcomes (1)

  • SARS CoV 2 IgG antibodies

    The presence or absence of SARS CoV 2 antibodies in serum of HCWs

    3 months

Study Arms (1)

Asymptomatic frontline HCWs for COVID 19

All healthcare workers who worked in high exposure areas of hospital dealing with COVID 19.

Diagnostic Test: IgG SARS CoV 2 antibodies

Interventions

IgG SARS CoV 2 antibodiesDIAGNOSTIC_TEST

The asymptomatic healthcare workers of high exposure COVID19 areas will be tested for IgG SARS CoV 2 antibodies

Asymptomatic frontline HCWs for COVID 19

Eligibility Criteria

Age20 Years - 60 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Healthcare workers who have been working in high exposure areas of COVID 19 and havenot developed disease themselves while working in that area

You may qualify if:

  • All HCWs who had been working in high exposure areas of COVID 19

You may not qualify if:

  • Any HCW of high exposure areas of COVID 19 who suffered from COVID 19 themselves diagnosed on PCR or clinically

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Lahore General Hospital

Lahore, Punjab Province, 54500, Pakistan

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Amina Asif, MPhilMicro

    LahoreGeneralHospital.Lahore

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER GOV
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Assistant Professor

Study Record Dates

First Submitted

September 20, 2020

First Posted

September 24, 2020

Study Start

July 1, 2020

Primary Completion

February 8, 2021

Study Completion

February 8, 2021

Last Updated

February 15, 2022

Record last verified: 2022-02

Locations

PA(1)