NCT04562844

Brief Summary

Patients who have suffered moderate to severe traumatic brain injury (TBI) frequently develop behavioural changes, which can have deleterious consequences on interpersonal relationships, social, family and professional reintegration. They are a source of difficulties (burden) for family and friends. Social cognition covers four functions: recognition of social cues; empathy; attribution of intentions to a third party, or theory of mind; and adjustment of social behaviour according to context. This study has two parts: 1/ Evaluation, using a cognitive approach, of the different components of social cognition after moderate to severe traumatic brain injury, and of its repercussions in daily life and on family and friends. 2/ Creation of a specific re-education method for the different modules of social cognition and study of its effectiveness.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
80

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Sep 2020

Longer than P75 for not_applicable

Geographic Reach
1 country

4 active sites

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

September 21, 2020

Completed
3 days until next milestone

First Posted

Study publicly available on registry

September 24, 2020

Completed
Same day until next milestone

Study Start

First participant enrolled

September 24, 2020

Completed
3 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 24, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2023

Completed
Last Updated

November 19, 2020

Status Verified

July 1, 2020

Enrollment Period

3 years

First QC Date

September 21, 2020

Last Update Submit

November 18, 2020

Conditions

Outcome Measures

Primary Outcomes (3)

  • social cognition evaluation

    emotional and sociocognitive measurement by questionnaire

    4 hours

  • humor and global cognition

    attention measurement and mood evolution by questionnaire

    4 hours

  • social activity measurement

    activity measurement and social cognition evaluation by questionnaire

    1 hour

Secondary Outcomes (3)

  • environnemental measurement

    20 min

  • mood measurement

    30 min

  • quality of life questionnaire

    1 hour

Study Arms (1)

Social cognition

EXPERIMENTAL
Other: sociale cognition

Interventions

several social cognition test

Social cognition

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Male or female of legal age,
  • Having suffered a moderate to severe traumatic brain injury (Glasgow Coma Scale score of 3 to 12) at least 6 months after the trauma,
  • Returned home at least 3 months ago,
  • Having given their informed consent,
  • Affiliated to the social security system

You may not qualify if:

  • Psychiatric history,
  • Persistent post-traumatic amnesia,
  • Instrumental disorders that interfere with taking tests (aphasia, agnosia, neurovisual disorders),
  • Mood disorders not stabilized under treatment,
  • Patient refuses to participate in the study,
  • Participation in another cognitive rehabiltation protocol,
  • Pregnant or breastfeeding woman.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

SAMSAH-UEROS Arceau Anjou

Angers, 49100, France

RECRUITING

Raymond Poincaré Hospital

Garches, 92380, France

NOT YET RECRUITING

Ueros Ugecam

Garches, 92380, France

NOT YET RECRUITING

FAM la vie devant soi

Lomme, 59160, France

RECRUITING

MeSH Terms

Conditions

Cognition Disorders

Condition Hierarchy (Ancestors)

Neurocognitive DisordersMental Disorders

Central Study Contacts

Isabelle Bossard, Msc

CONTACT

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
DIAGNOSTIC
Intervention Model
SINGLE GROUP
Model Details: single group for 1 study and multiples singles cases study for rehabilitation
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

September 21, 2020

First Posted

September 24, 2020

Study Start

September 24, 2020

Primary Completion

September 24, 2023

Study Completion

December 31, 2023

Last Updated

November 19, 2020

Record last verified: 2020-07

Data Sharing

IPD Sharing
Will not share

Locations