NCT04560530

Brief Summary

The role of CT scan of the chest in Pre-anesthetic assessment of the severity of COVID-19 and the correlations between CT measurements of the aortic and pulmonary arteries diameters and severity of pneumonia.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Mar 2020

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

March 1, 2020

Completed
5 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 30, 2020

Completed
1 month until next milestone

Study Completion

Last participant's last visit for all outcomes

September 1, 2020

Completed
21 days until next milestone

First Submitted

Initial submission to the registry

September 22, 2020

Completed
1 day until next milestone

First Posted

Study publicly available on registry

September 23, 2020

Completed
Last Updated

September 23, 2020

Status Verified

September 1, 2020

Enrollment Period

5 months

First QC Date

September 22, 2020

Last Update Submit

September 22, 2020

Conditions

Covid19

Outcome Measures

Primary Outcomes (4)

  • pneumonia severity.

    The pneumonia severity will be assessed by the radiologist.

    90 days

  • Aorta diameter

    Aorta cross sectional diameter will be calculated by using cursor method on CT scan

    90 days

  • Pulmonary artery diameter

    Pulmonary artery sectional diameter will be calculated by using cursor method on CT scan

    90 days

  • Pulmonary artery diameter TO Aorta diameter ratio

    Pulmonary artery diameter TO Aorta diameter ratio will be calculated

    90 days

Secondary Outcomes (1)

  • Description of the lesions found in the CT scan

    90 days

Interventions

Non-enhanced CT scan of the chestRADIATION

Non-enhanced CT scan of the chest with multi-slice CT scan machine.

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Patients who are older than 18 years, having confirmed or suspected COVID-19 infection and scheduled for emergency surgery.

You may qualify if:

  • All patients scheduled for emergency surgery with symptoms suggestive of COVID-19 infection.

You may not qualify if:

  • Pregnancy.
  • Haemodynamic instability (Mean arterial blood pressure above 65 mmHg or the need for of inotropic drugs to maintain mean arterial blood pressure above 65 mmHg).
  • Active bleeding.
  • Any indication by the surgeon or the anesthesiologist to proceed for immediate surgery for the patient safety.
  • Patients refusal to do CT scanning.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Security Forces Hospital

Riyadh, Saudi Arabia

Location

MeSH Terms

Conditions

COVID-19

Condition Hierarchy (Ancestors)

Pneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
ICU consultant

Study Record Dates

First Submitted

September 22, 2020

First Posted

September 23, 2020

Study Start

March 1, 2020

Primary Completion

July 30, 2020

Study Completion

September 1, 2020

Last Updated

September 23, 2020

Record last verified: 2020-09

Locations

SA(1)