Comparison of Acute Sauna With Exercise and Sauna

NCT04556422 | Completed

• 1 other identifier: Sauna
• Study Type: interventional
• Target: 72
• Locations: 1 country
• Sites: 1

Brief Summary

Sauna bathing has been associated with a lower risk for cardiovascular disease (CVD) outcomes, improved vascular endothelial and cardiac function, reduced oxidative stress and lower blood pressure. Earlier studies conducted by the investigators have showed positive alterations of arterial stiffness and hemodynamics through sauna bathing. Some studies have sought to utilize sauna bathing as an intervention after exercise with promising and synergistic results, although the effects on populations with cardiovascular risk factors are less clear. Furthermore, studies investigating the use of both exercise and sauna bathing in combination has been somewhat limited. However, results from some studies speculate that adjunctive exercise and sauna interventions may be useful for aging and clinical patient population groups. Given that heat therapy and sauna use is gaining more worldwide popularity, the investigators sought to compare the acute hemodynamic effects between sauna use alone and a short bout of exercise followed by sauna exposure. It was hypothesize that the combination of exercise and sauna will elicit greater changes than sauna alone. To achieve this, we standardized the protocol duration (30 minutes).

Conditions

Cardiovascular Risk Factor; Blood Pressure; Arterial Stiffness

Keywords

Sauna bathing; Aerobic exercise; Thermal therapy; Passive heat

Outcome Measures

Primary Outcomes (2)

• Brachial blood pressure

  Systolic and diastolic blood pressure

  Single session (30 minutes)

• Central blood pressure

  Systolic and diastolic blood pressure measured using ECG and Pulsepen

  Single session (30 minutes)

Secondary Outcomes (2)

• Arterial Stiffness

  Single session (30 minutes)

• Augmentation Index

  Single session (30 minutes)

Study Arms (2)

Sauna alone

ACTIVE COMPARATOR

Sauna exposure for 30 minutes

Other: Sauna bathing

Exercise and Sauna

EXPERIMENTAL

Cycling exercise for 15 minutes followed by sauna for 15 minutes

Other: Aerobic exercise; Other: Sauna bathing

Interventions

Aerobic exercise OTHER

15 minutes of aerobic exercise using stationary bicycle

Exercise and Sauna

Sauna bathing OTHER

Passive heat exposure

Exercise and Sauna; Sauna alone

Eligibility Criteria

• Age: 30 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Free of a prior diagnosis of CVD, exhibits at least one of the following cardiovascular risk factors: a history of smoking, hyperlipidemia, hypertension, diabetes, obesity, or family history of coronary heart disease (CHD).

You may not qualify if:

• recent musculoskeletal injuries or surgery (less than 6 months ago), mental illnesses, under 30 years of age or over 75 at time of recruitment, health conditions that may contraindicate study parameters.

Sponsors & Collaborators

• University of Jyvaskyla: lead
• Finnish Foundation for Cardiovascular Research: collaborator
• Business Finland: collaborator
• Harvia Finland Oy: collaborator

Study Sites (1)

University of Jyväskylä

Jyväskylä, Central Finland, 40014, Finland

Location

Related Publications (3)

• Lee E, Laukkanen T, Kunutsor SK, Khan H, Willeit P, Zaccardi F, Laukkanen JA. Sauna exposure leads to improved arterial compliance: Findings from a non-randomised experimental study. Eur J Prev Cardiol. 2018 Jan;25(2):130-138. doi: 10.1177/2047487317737629. Epub 2017 Oct 19.

  PMID: 29048215 BACKGROUND

• Laukkanen T, Kunutsor SK, Zaccardi F, Lee E, Willeit P, Khan H, Laukkanen JA. Acute effects of sauna bathing on cardiovascular function. J Hum Hypertens. 2018 Feb;32(2):129-138. doi: 10.1038/s41371-017-0008-z. Epub 2017 Dec 21.

  PMID: 29269746 BACKGROUND

• Lee E, Willeit P, Laukkanen T, Kunutsor SK, Zaccardi F, Khan H, Laukkanen JA. Acute effects of exercise and sauna as a single intervention on arterial compliance. Eur J Prev Cardiol. 2020 Jul;27(10):1104-1107. doi: 10.1177/2047487319855454. Epub 2019 Jun 8. No abstract available.

  PMID: 31177835 BACKGROUND

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Jari A Laukkanen, PhD/MD

  Central Finland Central Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: NONE
• Purpose: BASIC SCIENCE
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 14, 2020
• First Posted: September 21, 2020
• Study Start: August 1, 2018
• Primary Completion: October 30, 2018
• Study Completion: December 1, 2018
• Last Updated: September 23, 2020

Record last verified: 2020-09

Data Sharing

• IPD Sharing: Will not share

Locations

FI (1)