Evaluation of Factors That Cause Secondary Brain Damage on Mortality and Morbidity in Patients Undergoing Emergency Surgery Due to Head Trauma.

NCT04555772 | Completed

• 1 other identifier: uludagunineuroanesthesia
• Study Type: observational
• Target: 108
• Locations: 1 country
• Sites: 1

Brief Summary

Traumatic brain injury is combination damage that occurs as a result of a chain reaction of various metabolic events that develop after primary damage caused by trauma. Pathological events such as lactic acidosis, electrolyte imbalance, increased inflammation that occur during traumatic brain injury leads to poor prognosis in patients. The retrospective study was conducted to investigate the effect of factors that may cause secondary damage, especially electrolyte imbalance and blood glucose levels, on mortality and morbidity in patients undergoing emergency surgery due to head trauma.

Conditions

Brain Injuries

Keywords

secondary brain damage; electrolyte imbalance; head trauma

Outcome Measures

Primary Outcomes (1)

• mortality and morbidity in patients who underwent emergency operation within 24 hours after traumatic brain injury

  It seems that secondary damage caused by metabolic events like eletrolyte imbalance in patients with head trauma should always keep in mind. If they encounter these situations, they should treat the patient and do replacements immediately.

  5 years

Study Arms (3)

Healthy Group

Patients who had been treated and recovered physically and gained cognitive functions completely.

Other: factors evaluation

Sequel Group

Patients who could not gain their physical and cognitive functions.

Other: factors evaluation

Exitus Group

Patients who did not respond to the treatments and lost their lives within 28 days of admission.

Other: factors evaluation

Interventions

factors evaluation OTHER

They investigated mortality and morbidity in patients who underwent emergency operation within 24 hours after traumatic brain injury.

Exitus Group; Healthy Group; Sequel Group

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

they collect data of 108 patients who admitted to Bursa Uludag University hospital between 2013 and 2018 and were diagnosed with traumatic brain injury and operated within the first 24 hours after admission.

You may qualify if:

• patients who admitted to Bursa Uludag University hospital between 2013 and 2018
• patients diagnosed with traumatic brain injury and operated within the first 24 hours after admission

You may not qualify if:

• pediatric patients
• patients that operated after 24 hour of admission

Sponsors & Collaborators

• Turkish Society of Anesthesiology and Reanimation: lead

Study Sites (1)

Bursa uludag university

Bursa, 16285, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Brain Injuries; Craniocerebral Trauma

Condition Hierarchy (Ancestors)

Brain Diseases; Central Nervous System Diseases; Nervous System Diseases; Trauma, Nervous System; Wounds and Injuries

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 29, 2020
• First Posted: September 21, 2020
• Study Start: January 11, 2018
• Primary Completion: January 11, 2019
• Study Completion: January 30, 2019
• Last Updated: September 21, 2020

Record last verified: 2020-09

Data Sharing

• IPD Sharing: Will share

Locations

TU (1)