The Effect Of Low Back Pain on Paraspinal Muscles

NCT04555356 | Completed

• 1 other identifier: FSMTRHRF
• Study Type: observational
• Target: 205
• Locations: 1 country
• Sites: 1

Brief Summary

Low back pain is frequently seen in the adolescent age group, with a prevalence approaching that of the adult age group. The most common type is non-specific, self-limiting low back pain. LDH is rare in children and adolescents and generally presents with low back pain, with or without radiculopathy. The condition is usually unilateral (especially L4-5 or L5-S1). LDH is also mostly central type. Although there are many studies that have investigated the relationship between paraspinal muscle volumes and LBP and/or LDH in the adult age group, there are very few studies in adolescents. The principal aim of this study was to compare MF, ES, and PM volumes in adolescents with LBP with and without LDH using magnetic resonance imaging (MRI) and to determine whether these two conditions cause paraspinal muscle volume loss.

Conditions

Low Back Pain

Keywords

adolescent; low back pain; lumbar disc herniation; paraspinal muscle; magnetic resonance imaging

Outcome Measures

Primary Outcomes (1)

• Evaluation of paraspinal muscle volumes in adolescents with LBP with and without LDH

  Multifidus, erector spina and psoas major muscle volumes were measured using T2 weighted axial MR images at L4-5 and L5-S1 intervertebral disc levels.

  3 months

Eligibility Criteria

• Age: 10 Years - 18 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The patients (aged 10-17) with low back pain persisting for a minimum of twelve weeks

You may qualify if:

• Aged 10-18
• LBP persisting for a minimum of twelve weeks

You may not qualify if:

• spondylolysis-listhesis
• spinal alignment disorders including scoliosis and kyphosis
• inflammatory diseases
• histories of spinal surgery
• multilevel disc hernia

Sponsors & Collaborators

• Fatih Sultan Mehmet Training and Research Hospital: lead

Study Sites (1)

Fatih Sultan Mehmet Training and Research Hospital

Istanbul, Atasehir, 34758, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Low Back Pain; Intervertebral Disc Displacement

Condition Hierarchy (Ancestors)

Back Pain; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Spinal Diseases; Bone Diseases; Musculoskeletal Diseases; Hernia; Pathological Conditions, Anatomical

Study Officials

• Fatma Esra Bahadir Ulger

  Fatih Sultan Mehmet Training and Research Hospital

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 15, 2020
• First Posted: September 18, 2020
• Study Start: January 1, 2018
• Primary Completion: January 1, 2020
• Study Completion: January 1, 2020
• Last Updated: September 22, 2020

Record last verified: 2020-09

Locations

TU (1)