The Hybrid Combination of CCTA and SPECT and CAG for Evaluation Prognosis of CAD: an Observational Follow-up Study

NCT04554134 | Completed DMC

• 2 other identifiers: 2019-SR-242BK20141020
• Study Type: observational
• Target: 550
• Locations: 0 countries
• Sites: N/A

Brief Summary

A total of 550 patients with stable angina (40-70% stenosis) tested by coronary CT angiography (CCTA) and single photon emission computed tomography (SPECT) and coronary angiography (CAG) within 3 months were retrospectively recruited from 2005 to 2015 and follow up to 5 years. A new hybrid software was used to analysis the image data.

Conditions

Coronary Disease

Keywords

SPECT; CCTA; CAG; Hybrid

Outcome Measures

Primary Outcomes (1)

• Major adverse cardiac events (MACE)

  All-cause death, cardiac death, ischemic stroke, unplanned revascularization and nonfatal myocardial infarction

  5 YEARS

Eligibility Criteria

• Age: 18 Years - 90 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients who were suspected coronary artery disease and underwent CCTA, SPECT and CAG within 3 months from 2005 to 2015.

You may qualify if:

• Age: 18-70
• Gender: All
• coronary artery disease patients (CAD)
• underwent CCTA, SPECT and coronary angiography (CAG) together within 3 months
• Time: 2005-2015

You may not qualify if:

• dilated cardiomyopathy (DCM), hypertrophic cardiomyopathy (HCM), congenital heart disease (CHD), atrial fibrillation (AF), ventricular tachycardia (VT)
• Prior coronary revascularization;
• permanent pacemaker or internal defibrillator
• prosthetic heart valve
• coronary image lose
• coronary artery severe calcification
• motion artifacts and poor CCTA image quality

Sponsors & Collaborators

• The First Affiliated Hospital with Nanjing Medical University: lead
• Huai'an First People's Hospital: collaborator
• Changzhou No.2 People's Hospital: collaborator

MeSH Terms

Conditions

Coronary Disease

Condition Hierarchy (Ancestors)

Myocardial Ischemia; Heart Diseases; Cardiovascular Diseases; Vascular Diseases

Study Officials

• Yi Chai, MD

  The First Affiliated Hospital Hospital of Nanjing Medical University

  STUDY CHAIR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Director

Study Record Dates

• First Submitted: September 14, 2020
• First Posted: September 18, 2020
• Study Start: January 1, 2005
• Primary Completion: January 1, 2015
• Study Completion: February 1, 2020
• Last Updated: September 28, 2020

Record last verified: 2020-09

Data Sharing

• IPD Sharing: Will not share