Activity Breaks for Brain Health in Adolescents

NCT04552626 | Completed

• 1 other identifier: Dnr 2020-02597
• Study Type: interventional
• Target: 17
• Locations: 1 country
• Sites: 1

Brief Summary

The main aim for this study is to investigate to what extent physical activity of moderate or low intensity, relative to prolonged inactivity, may acutely alter neural activity-related prefrontal cortex oxygenated hemoglobin during a cognitive demanding task in 13- 15 year-old adolescents. The study is primarily focused on investigating these effects in ecologically valid conditions, i.e. activity patterns that closely resemble a typical day in school and using activity modes that are suitable in a school setting.

Conditions

Healthy Adolescents

Outcome Measures

Primary Outcomes (1)

• Changes in cerebral blood flow

  Oxygenated and deoxygenated hemoglobin concentration changes measured with functional near-infrared spectroscopy

  before to after 80 minutes intervention

Secondary Outcomes (6)

• Cognitive performance

  before and after 80 minutes intervention

• Augmentation index

  before and after 80 minutes intervention

• Cortisol

  morning; before and after 80 minutes intervention

• Mood

  at the beginning of the day; before and after 80 minutes intervention

• Sleepiness

  at the beginning of the day; before and after 80 minutes intervention

Study Arms (3)

Prolonged sitting (social breaks)

EXPERIMENTAL

Behavioral: Prolonged sitting (social breaks)

Prolonged sitting with step-up exercise break

EXPERIMENTAL

Behavioral: Prolonged sitting with step-up exercise break

Prolonged sitting with simple resistance activity breaks

EXPERIMENTAL

Behavioral: Prolonged sitting with simple resistance activity breaks

Interventions

Prolonged sitting (social breaks) BEHAVIORAL

Participants are required to sit for 80 minutes doing schoolwork, with a toilet break in between. Every twenty minutes participants will have a short social break. Test day begins at 8:00 with pretest measures, followed by the intervention at about 9:00, which will end around 12:00, with subsequent posttest measures.

Prolonged sitting (social breaks)

Prolonged sitting with step-up exercise break BEHAVIORAL

Participants are required to sit for 80 minutes doing schoolwork, with a toilet break in between. Every twenty minutes participants will have a physical activity break, where they will perform a simple moderate-intensity step-up exercise for three minutes at a predetermined pace. Test day begins at 8:00 with pretest measures, followed by the intervention at about 9:30, which will end around 12:00, with subsequent posttest measures.

Prolonged sitting with step-up exercise break

Prolonged sitting with simple resistance activity breaks BEHAVIORAL

Participants are required to sit for 80 minutes doing schoolwork, with a toilet break in between. Every twenty minutes participants will have a physical activity break, where they will perform simple resistance activities following a video for about three minutes. Test day begins at 8:00 with pretest measures, followed by the intervention at about 9:30, which will end around 12:00, with subsequent posttest measures.

Prolonged sitting with simple resistance activity breaks

Eligibility Criteria

• Age: 13 Years - 14 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17)

You may not qualify if:

• Ongoing medication that can affect central circulation or brain circulation
• Ongoing infection
• Inability to apprehend information about the study or to perform the tests

Sponsors & Collaborators

• The Swedish School of Sport and Health Sciences: lead
• The Knowledge Foundation: collaborator
• IKEA: collaborator
• Skandia: collaborator
• Konsumentföreningen Stockholm: collaborator
• Generation PEP: collaborator
• COOP: collaborator

Study Sites (1)

The Swedish School of Sport and Health Sciences (GIH)

Stockholm, 114 86, Sweden

Location

Related Publications (2)

• Kjellenberg K, Ekblom O, Tarassova O, Fernstrom M, Nyberg G, Ekblom MM, Helgadottir B, Heiland EG. Short, frequent physical activity breaks improve working memory while preserving cerebral blood flow in adolescents during prolonged sitting - AbbaH teen, a randomized crossover trial. BMC Public Health. 2024 Aug 2;24(1):2090. doi: 10.1186/s12889-024-19306-y.

  PMID: 39095724 DERIVED

• Heiland EG, Kjellenberg K, Tarassova O, Fernstrom M, Nyberg G, Ekblom MM, Helgadottir B, Ekblom O. ABBaH teens: Activity Breaks for Brain Health in adolescents: study protocol for a randomized crossover trial. Trials. 2022 Jan 6;23(1):22. doi: 10.1186/s13063-021-05972-5.

  PMID: 34991692 DERIVED

Study Officials

• Örjan Ekblom, PhD

  The Swedish School of Sport and Health Sciences

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: PREVENTION
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: September 10, 2020
• First Posted: September 17, 2020
• Study Start: September 17, 2020
• Primary Completion: December 16, 2020
• Study Completion: December 16, 2020
• Last Updated: February 24, 2021

Record last verified: 2021-02

Data Sharing

• IPD Sharing: Will not share

Locations

SE (1)