Level of Middle Cranial Fossa Dura in Patients With Cholesteatoma

NCT04551612 | Unknown

• 1 other identifier: Patients with Cholesteatoma
• Study Type: observational
• Target: 80
• Locations: 0 countries
• Sites: N/A

Brief Summary

Cholesteatoma is a destructive lesion that progressively expands in the middle ear, mastoid or petrous bone and leads to destruction of the nearby structures. Erosion, which is caused by bone resorption of the ossicular chain and otic capsule, may cause hearing loss, vestibular dysfunction, facial paralysis and intracranial manifestations

Conditions

Cholesteatoma, Middle Ear

Outcome Measures

Primary Outcomes (1)

• Evaluation of the Level of Middle Cranial Fossa Dura in Patients with Cholesteatoma by multislice computed tomography.

  determination the level of tegmen in patients with attico-antral diseases by MSCT

  One year

Study Arms (1)

Patients with cholesteatoma

Patients with cholesteatoma in one ear that will compared with the other healthy one.

Radiation: Multislice computed tomography temporal bone

Interventions

Multislice computed tomography temporal bone RADIATION

Patients with cholesteatoma will undergo multislice computed tomography (MSCT) temporal bone images. Then The Tegmen level will be determined and compared with the other normal ear at the same patient

Patients with cholesteatoma

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Patients with cholesteatoma in one ear

You may qualify if:

• All adults above the age of 18 presented to the Assiut university Clinic with
• cholesteatoma will be included in the study.

You may not qualify if:

• Patients with previous mastoid surgery
• Patients with Craniofacial anomalies or cleft lip and palate
• Pediatric populations ≤ 18 years old
• Patients with congenital ear anomalies

Sponsors & Collaborators

• Assiut University: lead

MeSH Terms

Conditions

Cholesteatoma, Middle Ear

Condition Hierarchy (Ancestors)

Ear Diseases; Otorhinolaryngologic Diseases; Cholesteatoma; Keratosis; Skin Diseases; Skin and Connective Tissue Diseases

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: September 10, 2020
• First Posted: September 16, 2020
• Study Start: October 1, 2020
• Primary Completion: October 1, 2021
• Study Completion: October 1, 2022
• Last Updated: September 17, 2020

Record last verified: 2020-09